{"id":"W2158058290","doi":"10.1136/ard.2008.099010","title":"Golimumab, a human antibody to tumour necrosis factor α given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study","year":2008,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":541,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Golimumab; Rheumatoid arthritis; Methotrexate; Rheumatoid factor; Immunology; Antibody; Internal medicine; Etanercept","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003422862,0.001327855,0.002872484,0.0005312248,0.0004017776,0.0004981513,0.0007680964,0.001309078,0.002183811],"category_scores_gemma":[0.0008753618,0.0005125541,0.001400925,0.0004415409,0.001053274,0.0005015671,0.0003254563,0.002051207,0.0006095227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005493828,"about_ca_system_score_gemma":0.001470585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009251372,"about_ca_topic_score_gemma":0.002200686,"domain_scores_codex":[0.9992529,0.0004269013,0.00002782966,0.00006692778,0.0001301112,0.00009539055],"domain_scores_gemma":[0.9992226,0.000185892,0.0001986797,0.00006058822,0.00005235663,0.000279826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8243381,0.05092385,0.0049236,0.001432627,0.001690228,0.0002523742,0.000179568,0.0009328193,0.02953235,0.0001460817,0.00215873,0.08348975],"study_design_scores_gemma":[0.6818359,0.307173,0.007359913,0.00004102202,0.0005079841,0.0001818316,0.00001781984,0.0002367271,0.001399796,0.00004907067,0.001183435,0.00001338421],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906055,0.00591419,0.0004103843,0.000409212,0.0001167074,0.001270584,0.0004939932,0.00006470061,0.0007147699],"genre_scores_gemma":[0.9846601,0.006303371,0.001631976,0.001280593,0.0005620397,0.002008208,0.001412167,0.00002026159,0.002121245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003422862,"threshold_uncertainty_score":0.01810199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03950382936973801,"score_gpt":0.3380614187487831,"score_spread":0.2985575893790451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}