{"id":"W2158114680","doi":"10.4049/jimmunol.1001725","title":"Granulysin Production and Anticryptococcal Activity Is Dependent upon a Far Upstream Enhancer That Binds STAT5 in Human Peripheral Blood CD4+ T Cells","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Enhancer; Biology; Granulysin; STAT5; Molecular biology; Transcription (linguistics); Transcription factor; Cell biology; In vitro; Cytotoxic T cell; Gene; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001436045,0.0002313624,0.0001904404,0.0002110442,0.0001059501,0.0002986191,0.00009546369,0.00019215,0.001683371],"category_scores_gemma":[0.0001229607,0.0001611148,0.0002493856,0.0001390814,0.0001604528,0.00009100576,0.0001806501,0.0004803902,0.0006164981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003287365,"about_ca_system_score_gemma":0.000199022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005866292,"about_ca_topic_score_gemma":0.0006435129,"domain_scores_codex":[0.999806,0.00003273368,0.00001631316,0.00005187963,0.00004282808,0.00005025939],"domain_scores_gemma":[0.9998926,0.00002552868,0.00002732793,0.00001431023,0.00001147834,0.00002879583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001492516,0.00001596157,0.0003182189,0.0000201651,0.000001862129,0.00003179345,0.00001488258,0.00003675836,0.9986834,0.00003360345,0.00001858188,0.0006754429],"study_design_scores_gemma":[0.00006282313,0.0004905037,0.03432127,0.00001692331,0.00002280647,0.0005040063,0.00004800633,0.001991316,0.9600046,0.00007184604,0.002458566,0.000007435774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917796,0.001890097,0.004401798,0.00006777094,0.00001939573,0.00003032144,0.0006366117,0.0001277309,0.001046526],"genre_scores_gemma":[0.9931203,0.0003626471,0.003103669,0.00005396051,0.00001158385,0.00002843083,0.001463915,0.00001442067,0.001841129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001683371,"threshold_uncertainty_score":0.005631506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009005066205920806,"score_gpt":0.234075465272334,"score_spread":0.2250703990664132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}