{"id":"W2158141040","doi":"10.1093/humrep/dep446","title":"What next for preimplantation genetic screening? A polar body approach!","year":2009,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Preimplantation genetic diagnosis; Polar body; Gynecology; Biology; Y chromosome; Genetics; Oocyte; Medicine; Pregnancy; Embryo; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006213037,0.001013129,0.001532503,0.001018262,0.001296764,0.002784602,0.001358599,0.00795459,0.01713087],"category_scores_gemma":[0.01032154,0.0003391567,0.001198209,0.0006379891,0.004193923,0.007146327,0.001583723,0.008730669,0.007638196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001095774,"about_ca_system_score_gemma":0.005039137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00235006,"about_ca_topic_score_gemma":0.005315802,"domain_scores_codex":[0.9977622,0.001061201,0.000173281,0.0002223716,0.0005445178,0.0002363601],"domain_scores_gemma":[0.9922841,0.003152174,0.0006282598,0.0005097273,0.001481397,0.001944476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001382594,0.0007615046,0.004021638,0.004245888,0.0001518555,0.001614168,0.0004393167,0.0003232184,0.002982729,0.02792404,0.3931669,0.562986],"study_design_scores_gemma":[0.0008381394,0.002074543,0.00659137,0.009552269,0.0003263399,0.005298947,0.003081247,0.0003997782,0.00141689,0.09559615,0.8745891,0.0002351188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.002196954,0.1347946,0.008098638,0.8161348,0.02487371,0.0002249047,0.0002107831,0.000216057,0.01324947],"genre_scores_gemma":[0.04329228,0.2653012,0.06214963,0.5382293,0.05157762,0.001306921,0.0004957604,0.0002796634,0.03736755],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01713087,"threshold_uncertainty_score":0.0573085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05134088297921184,"score_gpt":0.3130700662991197,"score_spread":0.2617291833199079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}