{"id":"W2158141040","doi":"10.1093/humrep/dep446","title":"What next for preimplantation genetic screening? A polar body approach!","year":2009,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Preimplantation genetic diagnosis; Polar body; Gynecology; Biology; Y chromosome; Genetics; Oocyte; Medicine; Pregnancy; Embryo; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002263291,0.0001240561,0.0001709014,0.00009940214,0.0001804446,0.0001238762,0.00005410691,0.00008126756,0.00001015],"category_scores_gemma":[0.0002508246,0.0001185717,0.0000770824,0.0001116423,0.00002895016,0.0003754345,0.00001068813,0.0001166526,0.000009286693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003006448,"about_ca_system_score_gemma":0.00001712707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003347389,"about_ca_topic_score_gemma":0.000001723839,"domain_scores_codex":[0.9988635,0.00002579145,0.0002211058,0.0004965303,0.0001883017,0.0002048241],"domain_scores_gemma":[0.9992279,0.00002316761,0.00009485146,0.0004572293,0.0001083692,0.0000885036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001802131,0.001422523,0.007848299,0.0005291989,0.0001979745,0.00003975682,0.001940537,0.001119457,0.1235313,0.004173786,0.01575402,0.841641],"study_design_scores_gemma":[0.004662826,0.004134167,0.9237775,0.0005571134,0.0007163548,0.001436126,0.001266476,0.00464553,0.03559328,0.005319898,0.01720682,0.0006838829],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9418691,0.002816575,0.05057838,0.001270399,0.0004789317,0.001541646,0.000006310212,0.0003683988,0.001070271],"genre_scores_gemma":[0.9753112,0.0001248888,0.02153846,0.0002630211,0.001424533,0.00004134332,0.0004413105,0.00001872399,0.0008365284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9159293,"threshold_uncertainty_score":0.4835212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05134088297921184,"score_gpt":0.3130700662991197,"score_spread":0.2617291833199079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}