{"id":"W2158214893","doi":"10.1128/cvi.00591-14","title":"Efficacy of Human Papillomavirus 16 and 18 (HPV-16/18) AS04-Adjuvanted Vaccine against Cervical Infection and Precancer in Young Women: Final Event-Driven Analysis of the Randomized, Double-Blind PATRICIA Trial","year":2015,"lang":"en","type":"article","venue":"Clinical and Vaccine Immunology","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"GlaxoSmithKline","keywords":"Medicine; Cohort; Vaccination; Confidence interval; Cervical cancer; Vaccine efficacy; HPV infection; Immunogenicity; Randomized controlled trial; Cervical intraepithelial neoplasia; Vaccine trial; HPV vaccines; Internal medicine; Young adult; Oncology; Gynecology; Cancer; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01137454,0.001764675,0.003319286,0.0004244948,0.0003083219,0.001186454,0.001069421,0.001414644,0.003180403],"category_scores_gemma":[0.009631296,0.0006557148,0.005470455,0.0004037597,0.000679338,0.0006700646,0.0006197577,0.001984313,0.0004475556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005377303,"about_ca_system_score_gemma":0.001231633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007194147,"about_ca_topic_score_gemma":0.001088277,"domain_scores_codex":[0.9917511,0.006581087,0.0003440533,0.0005304596,0.0004238706,0.0003694305],"domain_scores_gemma":[0.9956922,0.001873739,0.001063,0.0005662984,0.0004281236,0.000376628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9665104,0.001026344,0.002448753,0.001450645,0.00799166,0.00004852212,0.00005475723,0.0007740404,0.001315243,0.0001847583,0.001157133,0.01703779],"study_design_scores_gemma":[0.8962288,0.08030605,0.01090514,0.0001325398,0.00714742,0.00009893024,0.00002093961,0.001652847,0.00110197,0.0004012765,0.001973243,0.00003083485],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634849,0.01249252,0.003450995,0.0007687315,0.0005341543,0.01029868,0.005026841,0.0002389562,0.003704168],"genre_scores_gemma":[0.9764606,0.002602088,0.004378521,0.0008131674,0.0005142754,0.007607423,0.004084979,0.00004716309,0.003491902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01137454,"threshold_uncertainty_score":0.06015509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1191740909336267,"score_gpt":0.4325047168914288,"score_spread":0.3133306259578021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}