{"id":"W2158230043","doi":"10.1093/carcin/bgp254","title":"Loss of imprinting of the insulin-like growth factor II (IGF2) gene in esophageal normal and adenocarcinoma tissues","year":2009,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Saskatchewan Health Research Foundation","keywords":"Imprinting (psychology); Internal medicine; Esophageal cancer; Genomic imprinting; Medicine; Gastroenterology; Insulin-like growth factor 2; Adenocarcinoma; Esophageal disease; Gene expression; Esophagus; Cancer; Growth factor; Biology; Gene; DNA methylation; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002835917,0.0001691798,0.0002970304,0.0006093073,0.0001972414,0.000343114,0.0001630178,0.0001521876,0.0006297267],"category_scores_gemma":[0.0009352655,0.0001978104,0.0001506231,0.0004445971,0.0002684677,0.0002066229,0.0002559105,0.0001947223,0.0001303461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000204193,"about_ca_system_score_gemma":0.0001235864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001190509,"about_ca_topic_score_gemma":0.001232936,"domain_scores_codex":[0.9997969,0.00003464975,0.00002291341,0.00005713062,0.00004339567,0.00004500454],"domain_scores_gemma":[0.99949,0.0001772137,0.00015907,0.00004711522,0.00004255974,0.00008398828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000356848,0.00001260778,0.989707,0.00001174438,0.00002439608,0.000561978,0.00006160497,0.00005190579,0.007308185,0.00001089294,0.00002238397,0.001870446],"study_design_scores_gemma":[0.000006151315,0.0002027473,0.9946742,0.000001994236,0.00002198281,0.00313607,0.00009317153,0.0001804516,0.001498811,0.00001329636,0.0001685785,0.000002433181],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994705,0.0002153119,0.0001375504,0.000003435442,0.000001284305,0.000002333529,0.00007256096,0.000002703833,0.00009432359],"genre_scores_gemma":[0.9996567,0.00006107189,0.00008907432,0.000003868356,0.00000163774,0.000002722886,0.0001288267,0.00000124102,0.00005482061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001190509,"threshold_uncertainty_score":0.002367079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00875851256152868,"score_gpt":0.2193568262374987,"score_spread":0.21059831367597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}