{"id":"W2158291672","doi":"10.1111/j.1365-2125.2010.03722.x","title":"Fruit juice inhibition of uptake transport: a new type of food–drug interaction","year":2010,"lang":"en","type":"review","venue":"British Journal of Clinical Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":221,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Grapefruit juice; Fexofenadine; Bioavailability; Chemistry; Pharmacology; Orange juice; Drug interaction; Terfenadine; Naringin; Pharmacokinetic interaction; Food science; Pharmacokinetics; Naringenin; Celiprolol; Biochemistry; Chromatography; Flavonoid; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001760112,0.0002938329,0.004253736,0.000279506,0.00002837559,0.000005583905,0.000250779,0.0007485228,0.001400672],"category_scores_gemma":[0.000230379,0.000270769,0.002079768,0.0003286074,0.0002211256,0.0001305167,0.00001592053,0.003104007,0.000009626157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003603038,"about_ca_system_score_gemma":0.001830364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002233097,"about_ca_topic_score_gemma":0.00009667892,"domain_scores_codex":[0.9936984,0.0002731694,0.005015091,0.0002927229,0.0004647055,0.0002559761],"domain_scores_gemma":[0.994118,0.0004875842,0.004093425,0.0001530016,0.0007271345,0.0004209088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00117372,0.00106328,0.00002794061,0.008874438,0.001085162,0.001223354,0.00003379639,0.000001173929,0.000393285,0.00002070226,0.009062689,0.9770405],"study_design_scores_gemma":[0.003957964,0.001423823,0.0003785332,0.02322681,0.00771723,0.003341062,0.00001698994,8.2485e-7,0.0003827885,0.0001321224,0.9592245,0.0001973913],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02515513,0.9642906,0.0001634801,0.0001609308,0.00900939,0.0006206117,0.00008577236,0.00001327628,0.000500823],"genre_scores_gemma":[0.006408724,0.9887498,0.0009681146,0.00021165,0.002871351,0.000003513128,0.00006972614,0.00005868714,0.0006584594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9768431,"threshold_uncertainty_score":0.9999744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1305573143568796,"score_gpt":0.4607432538678388,"score_spread":0.3301859395109591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}