{"id":"W2158291672","doi":"10.1111/j.1365-2125.2010.03722.x","title":"Fruit juice inhibition of uptake transport: a new type of food–drug interaction","year":2010,"lang":"en","type":"review","venue":"British Journal of Clinical Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":221,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Grapefruit juice; Fexofenadine; Bioavailability; Chemistry; Pharmacology; Orange juice; Drug interaction; Terfenadine; Naringin; Pharmacokinetic interaction; Food science; Pharmacokinetics; Naringenin; Celiprolol; Biochemistry; Chromatography; Flavonoid; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000292764,0.0005263787,0.001146229,0.0006725739,0.0001673863,0.0008209778,0.0004323487,0.0007949265,0.002615001],"category_scores_gemma":[0.0003558483,0.0002011856,0.000950064,0.0006101697,0.0002587272,0.0009358712,0.0004070873,0.0007668085,0.000441139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003559662,"about_ca_system_score_gemma":0.0002794709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004463137,"about_ca_topic_score_gemma":0.0008847623,"domain_scores_codex":[0.9997317,0.00006078865,0.00003040107,0.00006296322,0.00008413013,0.00002993771],"domain_scores_gemma":[0.9998187,0.00007621372,0.0000468041,0.000007478071,0.00004246356,0.000008340053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009959575,0.0004112209,0.001887629,0.05386566,0.001321209,0.002485565,0.0003622557,0.001122942,0.1786676,0.005863546,0.01682734,0.736189],"study_design_scores_gemma":[0.000255356,0.004134288,0.01097244,0.002033026,0.001934798,0.005594991,0.0001882514,0.00106282,0.07088839,0.001955114,0.9008643,0.000116225],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01664946,0.9764855,0.002360653,0.0005249613,0.0004986041,0.0000660053,0.0001744248,0.00005806876,0.003182311],"genre_scores_gemma":[0.09166557,0.896531,0.003302444,0.001139043,0.0006638342,0.0001235438,0.0003708526,0.0000256761,0.006177951],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002615001,"threshold_uncertainty_score":0.008748055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1305573143568796,"score_gpt":0.4607432538678388,"score_spread":0.3301859395109591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}