{"id":"W2158371220","doi":"10.1093/annonc/mdh133","title":"A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1, 2 and 3 every 3 weeks in patients with solid cancers","year":2004,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Hamilton Regional Laboratory Medicine Program","funders":"National Cancer Institute","keywords":"Medicine; Cisplatin; Intravenous Infusions; Oncology; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009768694,0.00009940642,0.0002272407,0.00006607528,0.00002773412,0.000002742362,0.00006082057,0.00009538918,0.000005051211],"category_scores_gemma":[0.00001466545,0.00008745352,0.00001661357,0.00005923578,0.00007816256,0.000002878515,0.00005589665,0.00006788856,1.983028e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001837959,"about_ca_system_score_gemma":0.0001826093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004991827,"about_ca_topic_score_gemma":0.001007184,"domain_scores_codex":[0.9993491,0.00003563066,0.0001875314,0.0002026,0.00008057273,0.0001445821],"domain_scores_gemma":[0.9995853,0.0000132065,0.0001252864,0.0001391288,0.00008265555,0.00005437419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02292658,0.02791064,0.02397287,0.000147334,0.001078436,0.00007980308,0.01497931,0.001976898,0.5472773,0.001017504,0.0003252286,0.3583081],"study_design_scores_gemma":[0.0683929,0.4747071,0.1010248,0.0002154711,0.0001618947,0.00002139505,0.003269714,0.0000266887,0.3404535,0.001966196,0.009073318,0.0006870353],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989952,0.0001325696,0.000016724,0.0001521979,0.00004024338,0.0003187155,0.00002982339,0.000001534026,0.0003130286],"genre_scores_gemma":[0.9990178,0.0003615501,0.00006099981,0.0004864463,0.00001761484,0.00001783947,0.00001570791,0.000009769706,0.00001230595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4467964,"threshold_uncertainty_score":0.3566251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357478316002732,"score_gpt":0.3396303289529543,"score_spread":0.316055545792927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}