{"id":"W2158371220","doi":"10.1093/annonc/mdh133","title":"A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1, 2 and 3 every 3 weeks in patients with solid cancers","year":2004,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Hamilton Regional Laboratory Medicine Program","funders":"National Cancer Institute","keywords":"Medicine; Cisplatin; Intravenous Infusions; Oncology; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001569434,0.001850445,0.004153687,0.0007848096,0.0008068483,0.00133776,0.001431774,0.001629536,0.003272237],"category_scores_gemma":[0.001245914,0.001260149,0.002020913,0.001080319,0.002198619,0.001336719,0.0004680353,0.005656265,0.0009957203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001206619,"about_ca_system_score_gemma":0.003610794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002224577,"about_ca_topic_score_gemma":0.004051233,"domain_scores_codex":[0.9992393,0.000369002,0.00002919539,0.0001165469,0.00004506347,0.0002009712],"domain_scores_gemma":[0.9988486,0.0002346867,0.000142159,0.000130616,0.000052405,0.0005915788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8378041,0.07127827,0.003593059,0.0004668409,0.0006844823,0.0002003856,0.000361995,0.003137664,0.02477338,0.0004989522,0.002198464,0.0550025],"study_design_scores_gemma":[0.4762762,0.5147066,0.00393478,0.00001926966,0.0002917681,0.0001335317,0.00007224968,0.0006891431,0.002228269,0.000148677,0.001468389,0.00003115381],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935289,0.001399318,0.0004724133,0.0004726258,0.0001810395,0.001886281,0.0005725446,0.00007893283,0.001407876],"genre_scores_gemma":[0.9881142,0.002161351,0.001958692,0.0006316289,0.0002883519,0.002950467,0.00154787,0.00004993545,0.002297537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004153687,"threshold_uncertainty_score":0.01094669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357478316002732,"score_gpt":0.3396303289529543,"score_spread":0.316055545792927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}