{"id":"W2158372697","doi":"10.1016/j.canep.2010.06.012","title":"Nrf2–ARE signaling pathway and natural products for cancer chemoprevention","year":2010,"lang":"en","type":"review","venue":"Cancer Epidemiology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Natural Science Foundation of Shandong Province; Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"KEAP1; Transcription factor; Enzyme; Carcinogen; Signal transduction; Cancer; Cell biology; Gene; Medicine; Biochemistry; Biology; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006613087,0.0005361662,0.00176486,0.00005874828,0.0001112116,0.00001105748,0.0003333745,0.000954529,0.00001493254],"category_scores_gemma":[0.001201765,0.0004533163,0.0004132263,0.00006730829,0.000263999,0.000004572208,0.0001753065,0.0005329851,0.000003058681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006949839,"about_ca_system_score_gemma":0.0003899823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003627512,"about_ca_topic_score_gemma":0.0001193489,"domain_scores_codex":[0.9971834,0.0002705349,0.0007304673,0.001197441,0.00004940075,0.0005686876],"domain_scores_gemma":[0.9980349,0.000220541,0.0009172359,0.0004825915,0.0002348106,0.00010991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000063566,0.0000363443,0.0002882486,0.01415187,0.0004602031,0.000001057582,0.00002079408,0.00000386622,0.04952101,0.0001059167,0.006968015,0.9283791],"study_design_scores_gemma":[0.000262966,0.00005316091,0.00002757274,0.001577113,0.0002918192,0.000009936,0.000006769833,0.00000399491,0.01730606,0.0003304161,0.9796253,0.0005049078],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001893424,0.9938615,0.0002121422,0.0003633221,0.001840713,0.001183594,0.0006168116,0.00001537454,0.00001310006],"genre_scores_gemma":[0.0004827206,0.9896317,0.001357308,0.0004226194,0.004067536,0.001635949,0.001316632,0.00008566184,0.0009998436],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9726573,"threshold_uncertainty_score":0.9997919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07474048341623325,"score_gpt":0.3897105090247813,"score_spread":0.3149700256085481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}