{"id":"W2158401328","doi":"10.1017/s146239940800077x","title":"Critical molecular abnormalities in high-grade serous carcinoma of the ovary","year":2008,"lang":"en","type":"review","venue":"Expert Reviews in Molecular Medicine","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; BC Cancer Agency","funders":"Eli Lilly Canada; Michael Smith Health Research BC; National Cancer Institute; Sanofi","keywords":"CDKN2A; Serous fluid; Serous carcinoma; Ovarian carcinoma; Carcinogenesis; Biology; Ovarian cancer; Cancer research; Ovary; Serous ovarian cancer; Pathology; Carcinoma; Clear cell carcinoma; Oncology; Gene; Cancer; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006223068,0.0008997436,0.005784824,0.0004874641,0.00004284965,0.000006942267,0.0005286117,0.0004488692,0.0001922618],"category_scores_gemma":[0.001026124,0.0005099971,0.001059126,0.001229238,0.0005967547,0.00004987094,0.0001880944,0.0009461588,0.0000179226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006050993,"about_ca_system_score_gemma":0.0005475357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146342,"about_ca_topic_score_gemma":0.00002833084,"domain_scores_codex":[0.9940566,0.00117922,0.002457471,0.0008459422,0.0008451845,0.000615554],"domain_scores_gemma":[0.997112,0.0003338007,0.0004836324,0.001750548,0.00009537006,0.0002246594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004104161,0.001665713,0.0008829817,0.05318022,0.0004624779,0.01491285,0.001552289,0.000001764515,0.00007828011,0.005417794,0.008788964,0.9130156],"study_design_scores_gemma":[0.001792293,0.0003434317,0.0004339051,0.1141949,0.0007339529,0.00114995,0.00004445421,0.000001619184,0.0001176117,0.00007635322,0.8807241,0.0003874658],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001382963,0.9924925,0.00005011756,0.002493034,0.000616919,0.003266912,0.00001449751,0.00001659398,0.0009111508],"genre_scores_gemma":[0.001128841,0.9936295,0.001031914,0.002362667,0.000284164,0.001288299,0.00009093006,0.0001168549,0.00006690128],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9126282,"threshold_uncertainty_score":0.9997352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05076582429117064,"score_gpt":0.3699778757065846,"score_spread":0.319212051415414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}