{"id":"W2158401596","doi":"10.1128/iai.69.5.3476-3482.2001","title":"<i>Escherichia coli</i>Heat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin","year":2001,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cholera toxin; Heat-labile enterotoxin; Enterotoxin; Adjuvant; Biology; Microbiology; Escherichia coli; Recombinant DNA; Immunogenicity; Antibody; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005019869,0.0002375872,0.0002566468,0.00007411223,0.0004007732,0.00003923114,0.0002226767,0.0002022076,0.00007948007],"category_scores_gemma":[0.0002186812,0.0001838656,0.0001322172,0.0003840194,0.0003393649,0.00001766172,0.0003347053,0.0004856676,0.00001177809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002901005,"about_ca_system_score_gemma":0.00008109675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001484086,"about_ca_topic_score_gemma":0.00027094,"domain_scores_codex":[0.9984323,0.0004123511,0.0003338938,0.0002767698,0.0002039104,0.0003408114],"domain_scores_gemma":[0.9989545,0.00004561321,0.0001146256,0.0004851222,0.0002991902,0.0001009226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004170926,0.0006023577,0.06676355,0.00006893765,0.0003558909,0.00000875758,0.001308957,0.00003332843,0.9266837,0.00004314461,0.001265075,0.002449249],"study_design_scores_gemma":[0.002210283,0.001607002,0.6601406,0.00006267518,0.00007733316,0.00009673251,0.000605538,0.0005355671,0.2358201,0.00005071533,0.09836735,0.0004261057],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946652,0.001554753,0.00005115746,0.0009825118,0.0001456779,0.0005650684,0.00003698126,0.00003177661,0.001966866],"genre_scores_gemma":[0.9927118,0.005199734,0.00002356043,0.0005874044,0.00006015815,0.0001014647,0.00006397975,0.00002454844,0.00122736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6908635,"threshold_uncertainty_score":0.7497821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01578910699725701,"score_gpt":0.2724611636027376,"score_spread":0.2566720566054806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}