{"id":"W2158401596","doi":"10.1128/iai.69.5.3476-3482.2001","title":"<i>Escherichia coli</i>Heat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin","year":2001,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cholera toxin; Heat-labile enterotoxin; Enterotoxin; Adjuvant; Biology; Microbiology; Escherichia coli; Recombinant DNA; Immunogenicity; Antibody; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002390585,0.0001848781,0.0001625309,0.0001178148,0.00006657041,0.0003447662,0.00006942623,0.0001867608,0.0007662647],"category_scores_gemma":[0.0001655255,0.00007777248,0.00009707198,0.0001015365,0.0001469753,0.000184731,0.00009406235,0.0002797817,0.0002128618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001152926,"about_ca_system_score_gemma":0.0001232215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001369503,"about_ca_topic_score_gemma":0.000206701,"domain_scores_codex":[0.9999112,0.00002788802,0.000006654224,0.00001422705,0.00001856577,0.00002147238],"domain_scores_gemma":[0.9998978,0.00003070691,0.00003321475,0.000006684136,0.00001205264,0.00001945507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004977467,0.00001168088,0.000254202,0.00002409219,0.00000182885,0.0000119251,0.000002864198,0.00002750143,0.9990807,0.00003959367,0.000004725958,0.0004911399],"study_design_scores_gemma":[0.0000120686,0.0007223085,0.004950535,0.000008180727,0.00001232639,0.0002779153,0.00002272938,0.0001674851,0.9921994,0.00005651849,0.001568185,0.000002389257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968145,0.001417406,0.001199481,0.00005634757,0.000006681259,0.000008299909,0.00004119823,0.000009379304,0.000446738],"genre_scores_gemma":[0.9955455,0.0008913366,0.002390878,0.00005643901,0.0000114354,0.000006938195,0.0001925229,0.000006604265,0.0008983827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007662647,"threshold_uncertainty_score":0.002563477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01578910699725701,"score_gpt":0.2724611636027376,"score_spread":0.2566720566054806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}