{"id":"W2158442510","doi":"10.3109/13550280903473452","title":"A limited innate immune response is induced by a replication-defective herpes simplex virus vector following delivery to the murine central nervous system","year":2009,"lang":"en","type":"article","venue":"Journal of NeuroVirology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; Burroughs Wellcome Fund; University of California, Irvine; Ryerson University","keywords":"Biology; Herpes simplex virus; Viral replication; Virology; Viral vector; Immune system; Vector (molecular biology); Chemokine; Innate immune system; Virus; Immunology; Gene; Recombinant DNA; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002869742,0.000420927,0.0003574842,0.0003366709,0.0002234353,0.0005271615,0.0002266785,0.0005920556,0.001311504],"category_scores_gemma":[0.0002432574,0.0002063089,0.0005021536,0.0001439073,0.0005214101,0.0004718643,0.0002850455,0.00140473,0.0003373769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004855859,"about_ca_system_score_gemma":0.0003974951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003503596,"about_ca_topic_score_gemma":0.0004945462,"domain_scores_codex":[0.9996002,0.00005539945,0.00004016663,0.00008526353,0.00006695718,0.0001520341],"domain_scores_gemma":[0.9996471,0.00005505118,0.0001341077,0.00004323564,0.00003605349,0.00008443584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004078352,0.00006526965,0.0001806243,0.00003695622,0.000006273788,0.0001362683,0.00002409399,0.00003534461,0.9982198,0.0001747443,0.00004038826,0.0006723511],"study_design_scores_gemma":[0.00006278781,0.001136769,0.006924947,0.00001930322,0.00004167822,0.00050681,0.0001374953,0.000769252,0.9894865,0.0001721298,0.0007322346,0.0000102462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970799,0.0008838297,0.000979765,0.00009030555,0.0000534757,0.00003366125,0.0001998583,0.00004427714,0.0006349358],"genre_scores_gemma":[0.9969132,0.0003422963,0.0009049312,0.00006065283,0.00001224449,0.00004348857,0.0002389263,0.00001555835,0.001468591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311504,"threshold_uncertainty_score":0.004387438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739068869296746,"score_gpt":0.2850953889359957,"score_spread":0.2677047002430283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}