{"id":"W2158442971","doi":"10.1038/nprot.2008.183","title":"Electrical stimulation systems for cardiac tissue engineering","year":2009,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":536,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Institute of Biomedical Imaging and Bioengineering; University of Toronto; Arthritis Foundation","keywords":"Tissue engineering; Pulsatile flow; Biomedical engineering; Stimulation; Cell culture; Cell; Substrate (aquarium); Functional electrical stimulation; Cell biology; Materials science; Nanotechnology; Biophysics; Computer science; Chemistry; Neuroscience; Biology; Medicine; Cardiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002188626,0.0001739724,0.0001543918,0.0001865953,0.0001854153,0.000317244,0.000215349,0.0003871724,0.003165212],"category_scores_gemma":[0.0002702392,0.0001102843,0.0001262397,0.0001462391,0.0002271008,0.0004315391,0.0003413896,0.0003442262,0.0006941245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001437685,"about_ca_system_score_gemma":0.00009765029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005630796,"about_ca_topic_score_gemma":0.000140874,"domain_scores_codex":[0.999903,0.00002271915,0.000008749226,0.00001937206,0.00003713023,0.000009058312],"domain_scores_gemma":[0.9999342,0.00003142992,0.00001135364,0.00000740843,0.000009869879,0.000005712781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006404341,0.00002503877,0.00008594894,0.0002706543,0.000009818884,0.00007853792,0.00004754298,0.0005400963,0.9437738,0.005051081,0.001383889,0.04866955],"study_design_scores_gemma":[0.00005905125,0.0005683447,0.001178559,0.00007971337,0.00003495472,0.000903323,0.00005620552,0.006512522,0.8998285,0.005645874,0.08510277,0.00003013386],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.4207,0.08487473,0.412001,0.00351764,0.002887964,0.0004845622,0.0008425501,0.001245626,0.07344586],"genre_scores_gemma":[0.8909808,0.01866329,0.06488369,0.0009305408,0.0003804156,0.000401651,0.0004277726,0.00009051341,0.02324141],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.003165212,"threshold_uncertainty_score":0.01058871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246891885275006,"score_gpt":0.3396462018993281,"score_spread":0.327177283046578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}