{"id":"W2158515573","doi":"10.1111/j.1582-4934.2008.00217.x","title":"Nitric oxide decreases the excitability of interstitial cells of Cajal through activation of the BK channel","year":2008,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Depolarization; BK channel; Chemistry; Nitric oxide; Biophysics; Sodium nitroprusside; Interstitial cell of Cajal; Patch clamp; Extracellular; Electrophysiology; Internal medicine; Membrane potential; Medicine; Biology; Immunohistochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001985464,0.0001743354,0.0002391199,0.0001307431,0.0001452108,0.0002179538,0.0001857076,0.0001453747,0.0005568274],"category_scores_gemma":[0.0003587012,0.00009145274,0.0001541069,0.00006808338,0.0002567368,0.0003425538,0.0002387215,0.0003022844,0.00006782268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009776965,"about_ca_system_score_gemma":0.0001821897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002633673,"about_ca_topic_score_gemma":0.000532766,"domain_scores_codex":[0.9998806,0.00002244745,0.00001696636,0.00002535651,0.00002382589,0.00003090907],"domain_scores_gemma":[0.9997762,0.00004630116,0.00006799088,0.00002095257,0.00002770858,0.00006094234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002371576,0.0000197063,0.001067506,0.00004921774,0.000005062363,0.00005990624,0.00003729676,0.00001892294,0.9971144,0.00005399205,0.00001503082,0.001321734],"study_design_scores_gemma":[0.00009332687,0.001290646,0.1145249,0.00002714765,0.0001059778,0.0006296408,0.000252964,0.001745302,0.8779901,0.0004218944,0.002905868,0.00001207451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970303,0.001415215,0.0008274463,0.00006377299,0.00002632064,0.000005728545,0.00002931612,0.00002729115,0.0005748315],"genre_scores_gemma":[0.9968652,0.0009468655,0.001364934,0.00003852041,0.00003371326,0.0000205022,0.00005225618,0.00000888285,0.0006690297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005568274,"threshold_uncertainty_score":0.001862764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01896522731127821,"score_gpt":0.2408745420536911,"score_spread":0.2219093147424129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}