{"id":"W2158526606","doi":"10.1128/mcb.24.7.2767-2778.2004","title":"The Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Biology; Integral membrane protein; Sec61; Cell biology; STIM1; Ubiquitin; Membrane protein; Vesicle-associated membrane protein 8; Chaperone (clinical); Biochemistry; Translocon; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003218438,0.0003058458,0.0003488145,0.00003794835,0.0001835552,0.00003231849,0.0004422734,0.0001819819,0.00002094783],"category_scores_gemma":[0.000257329,0.000202661,0.0002705731,0.0001542553,0.0008353032,0.000006387746,0.000336574,0.0001617171,0.000003550897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001634859,"about_ca_system_score_gemma":0.0001823101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000360922,"about_ca_topic_score_gemma":0.0001035713,"domain_scores_codex":[0.998095,0.0002405957,0.0005052586,0.0005039733,0.0002371706,0.0004180312],"domain_scores_gemma":[0.9985798,0.00001572778,0.000371809,0.0007503263,0.0001610728,0.0001212574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002844401,0.0001241574,0.0003522987,0.00006015708,0.000161089,0.00001855892,0.00002223552,0.00005312695,0.9923475,0.006332899,0.00004608217,0.0001974156],"study_design_scores_gemma":[0.001993751,0.0003665363,0.0002505846,0.0001246814,0.00009199242,0.00002658405,0.0000509693,0.00002055205,0.9935885,0.002148411,0.001104913,0.0002325384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911296,0.006636628,0.0003194715,0.0002650368,0.000111224,0.0009116149,0.0003238071,0.00001170387,0.0002908557],"genre_scores_gemma":[0.9988473,0.00008200923,0.00007533955,0.000110648,0.00004080827,0.0000811459,0.0003304744,0.00003546271,0.000396793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007717661,"threshold_uncertainty_score":0.8264277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003371598713417578,"score_gpt":0.2052724274795049,"score_spread":0.2019008287660873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}