{"id":"W2158526606","doi":"10.1128/mcb.24.7.2767-2778.2004","title":"The Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Biology; Integral membrane protein; Sec61; Cell biology; STIM1; Ubiquitin; Membrane protein; Vesicle-associated membrane protein 8; Chaperone (clinical); Biochemistry; Translocon; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001752021,0.0003811387,0.0004328751,0.0004721296,0.0002348808,0.000409145,0.0002588108,0.0004640066,0.001349361],"category_scores_gemma":[0.0001553973,0.0002089155,0.0003077554,0.0003538641,0.0002074625,0.0001666949,0.0003527714,0.000363678,0.0006514685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003122057,"about_ca_system_score_gemma":0.0001522901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004000112,"about_ca_topic_score_gemma":0.0006173304,"domain_scores_codex":[0.9997906,0.00002504976,0.00001761711,0.00004671435,0.00008725925,0.00003277697],"domain_scores_gemma":[0.9998348,0.00004538974,0.00003594105,0.00001511019,0.00001692371,0.00005183172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006504055,0.00001351332,0.0003550718,0.00001189644,0.000006095348,0.000222544,0.000004455495,0.00004231079,0.9987663,0.00003323157,0.00002918583,0.0004504649],"study_design_scores_gemma":[0.00001564784,0.0001573044,0.009545072,0.000002213113,0.00002216352,0.001755389,0.00002879594,0.001616973,0.9854398,0.00004805265,0.001362259,0.00000629657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905191,0.001123299,0.005981891,0.0001028259,0.00001692227,0.00003184992,0.001014561,0.0002301155,0.0009795767],"genre_scores_gemma":[0.9902856,0.0006820221,0.004659291,0.00006345803,0.00000576125,0.00002522312,0.002301061,0.00004150814,0.001936158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001349361,"threshold_uncertainty_score":0.004514039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003371598713417578,"score_gpt":0.2052724274795049,"score_spread":0.2019008287660873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}