{"id":"W2158529706","doi":"10.1128/jvi.75.15.7210-7214.2001","title":"Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"Wellcome Trust","keywords":"Biology; Adenoviridae; Mutant; Binding site; Receptor; Fiber; Virology; Molecular biology; Biophysics; Biochemistry; Chemistry; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009855838,0.000431838,0.0006465557,0.0003191178,0.0001907016,0.0000478564,0.001040126,0.0004694147,0.003074525],"category_scores_gemma":[0.0002164455,0.0002977824,0.0002721459,0.0006184693,0.0003788635,0.00002675533,0.000247474,0.0007333438,0.0005657526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009475624,"about_ca_system_score_gemma":0.0005053357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000131638,"about_ca_topic_score_gemma":0.0009332161,"domain_scores_codex":[0.9967994,0.0005298048,0.0007745699,0.0004881733,0.0006429281,0.0007650958],"domain_scores_gemma":[0.997511,0.0001192896,0.0006214674,0.0008292815,0.0006048281,0.000314132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02462464,0.0003415897,0.004449739,0.00001646967,0.000652661,0.00007212764,0.0002239879,0.0008959062,0.9574788,0.000007030667,0.008524642,0.002712404],"study_design_scores_gemma":[0.002579175,0.02211929,0.003054952,0.00006827295,0.0001587567,0.0005409255,0.000142462,0.00001074667,0.6698075,0.0000248504,0.3009498,0.0005432722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948652,0.002027167,0.00004352057,0.001185387,0.0004154696,0.000384081,0.00007465754,0.00001253759,0.0009919533],"genre_scores_gemma":[0.9919966,0.0005600846,0.0004492233,0.001057821,0.001117143,0.00001845867,0.0000161004,0.0001273996,0.004657184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2924252,"threshold_uncertainty_score":0.9999474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02314280740275875,"score_gpt":0.2936240725430692,"score_spread":0.2704812651403104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}