{"id":"W2158698966","doi":"10.1139/y05-018","title":"Proanthocyanidin from grape seeds enhances doxorubicin-induced antitumor effect and reverses drug resistance in doxorubicin-resistant K562/DOX cells","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Science Foundation of Gansu Province","keywords":"Doxorubicin; Pharmacology; Chemistry; Growth inhibition; K562 cells; Apoptosis; Biochemistry; Biology; Chemotherapy; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124141,0.0003602149,0.0003424754,0.0001635938,0.0000896624,0.0001607954,0.0001009341,0.000173865,0.0005929662],"category_scores_gemma":[0.00007505607,0.0001123419,0.0001932038,0.00009570661,0.0001201156,0.0001247035,0.0001078043,0.0003288368,0.0001938433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001317097,"about_ca_system_score_gemma":0.0001297721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004211078,"about_ca_topic_score_gemma":0.0007008728,"domain_scores_codex":[0.9999294,0.00001718765,0.000007414699,0.00001301438,0.00001739029,0.00001556069],"domain_scores_gemma":[0.999956,0.000007602646,0.00000924356,0.000006884748,0.00000549887,0.0000146641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008249554,0.00002295919,0.00006950639,0.00002357645,0.000002028058,0.0000226715,0.000005107711,0.00002514624,0.9992879,0.000009778942,0.00001073728,0.0004381629],"study_design_scores_gemma":[0.00003228326,0.0006578026,0.004619812,0.0000037249,0.00001189278,0.0001672912,0.00001017207,0.0006385267,0.9929825,0.00001394093,0.0008589752,0.000003157844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978238,0.000839906,0.0005174306,0.00003717949,0.00001610254,0.00001690579,0.00007156379,0.00003881135,0.0006383362],"genre_scores_gemma":[0.9964328,0.0005540202,0.001458273,0.00003068823,0.00001015723,0.00002126174,0.0002064544,0.00001113777,0.001275145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005929662,"threshold_uncertainty_score":0.001983702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008622786875244271,"score_gpt":0.2597883769029998,"score_spread":0.2511655900277556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}