{"id":"W2158824170","doi":"10.4161/cc.8.13.8883","title":"Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression","year":2009,"lang":"en","type":"article","venue":"Cell Cycle","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Biology; microRNA; Ectopic expression; RNA interference; Cadherin; Transfection; Messenger RNA; Cell biology; Cell culture; Transcription factor; Endogeny; Molecular biology; Cancer research; Genetics; Gene; Cell; RNA; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001008169,0.0001391228,0.000141665,0.00004425227,0.00006394503,0.0000148961,0.0001240511,0.0001310957,0.00005759816],"category_scores_gemma":[0.00001861017,0.0001324791,0.0000496762,0.00008175933,0.00003546826,0.000006576948,0.0001076357,0.00004492591,0.000008712932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001673371,"about_ca_system_score_gemma":0.00002637101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008855025,"about_ca_topic_score_gemma":0.000001533215,"domain_scores_codex":[0.9990202,0.00003954962,0.0002090145,0.0003686335,0.0001516876,0.0002109686],"domain_scores_gemma":[0.9992357,0.000005016779,0.00009816498,0.0004509035,0.0000636202,0.0001466194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001423561,0.0001176138,0.00036092,0.00003043108,0.00000239368,0.000001408478,0.0001721931,0.0003255849,0.9879286,0.000002862228,0.01037596,0.0005396632],"study_design_scores_gemma":[0.0004435019,0.0001897631,0.01125499,0.00006797201,0.00000858085,0.000001544436,0.0000474297,0.00009249661,0.9750679,0.0000523417,0.01262075,0.0001527459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967893,0.001447549,0.0004636899,0.0001047114,0.00005104643,0.0002306675,0.00002160171,0.00001313642,0.0008782598],"genre_scores_gemma":[0.9967014,0.00005554483,0.001850283,0.000142418,0.00006290813,0.000006375816,0.00005284981,0.00001730012,0.001110898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01286072,"threshold_uncertainty_score":0.5402343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006729495029617919,"score_gpt":0.2307193882233139,"score_spread":0.223989893193696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}