{"id":"W2158923767","doi":"10.1371/journal.ppat.1005187","title":"The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; University of Saskatchewan; McGill University Health Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Radboud Universiteit; University of Aberdeen; Canadian Institutes of Health Research; McGill University Health Centre; McGill University; Dartmouth College","keywords":"Aspergillus fumigatus; Virulence; Microbiology; Aspergillus nidulans; Biology; Neutrophil extracellular traps; Extracellular; Heterologous; NADPH oxidase; In vitro; Gene; Cell biology; Biochemistry; Enzyme; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001604532,0.0003583992,0.0001462421,0.0001212563,0.00006580757,0.0002619837,0.0001184302,0.0001840954,0.0006173471],"category_scores_gemma":[0.0001071314,0.00005735132,0.0001245754,0.00005277186,0.0001235564,0.0001698376,0.0002890685,0.0002998401,0.0001447682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306181,"about_ca_system_score_gemma":0.0001208092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002199991,"about_ca_topic_score_gemma":0.000336947,"domain_scores_codex":[0.9998863,0.00003589193,0.000007858886,0.00001205119,0.00002605055,0.00003183657],"domain_scores_gemma":[0.9999069,0.00001281417,0.00002667434,0.000008561692,0.00001362148,0.0000314118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005703579,0.0000172072,0.0003852406,0.00002608026,0.000003194992,0.00004425178,0.000007428494,0.0000271419,0.9979298,0.00007493689,0.00002264711,0.00140513],"study_design_scores_gemma":[0.00002892641,0.0008974498,0.02441669,0.0000211545,0.00002562704,0.0006450771,0.00006715184,0.001214399,0.9686351,0.0002071638,0.003832924,0.000008154814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915369,0.003887278,0.00289612,0.0001604739,0.00002386497,0.00002755941,0.0000927847,0.00006082613,0.001314164],"genre_scores_gemma":[0.9974229,0.0007886438,0.0009663371,0.00003010803,0.000006471178,0.000007462216,0.00005532984,0.000002942133,0.0007198538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006173471,"threshold_uncertainty_score":0.002065241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02134683537213778,"score_gpt":0.2250452108891833,"score_spread":0.2036983755170455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}