{"id":"W2158946650","doi":"10.1016/j.jalz.2013.08.140","title":"P4‐359: Effects of oral ELND005 (Scyllo‐inositol) on brain scyllo‐inositol and myo‐inositol levels: Spectroscopy results from a phase 2 study in MILD‐TO‐MODERATE Alzheimer's disease","year":2012,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Phytase and its Applications","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"","keywords":"Inositol; Chemistry; Internal medicine; Receptor; Endocrinology; Medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003573469,0.0009764628,0.001545125,0.0003631503,0.0003012576,0.0004047399,0.0006234017,0.001027016,0.003457905],"category_scores_gemma":[0.0003763811,0.0003624149,0.0007319514,0.0001999157,0.000647955,0.0005013427,0.0002444786,0.001557395,0.0006713968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000507378,"about_ca_system_score_gemma":0.0005167809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001724237,"about_ca_topic_score_gemma":0.003042386,"domain_scores_codex":[0.999862,0.00004113553,0.00001156224,0.00002446064,0.00001828373,0.00004259653],"domain_scores_gemma":[0.9998122,0.00003469691,0.00002519016,0.0000175533,0.0000127571,0.00009765825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6500131,0.06857657,0.003656125,0.0007177261,0.0008933482,0.0005836152,0.0001779815,0.0008925894,0.1880904,0.0001247617,0.002058271,0.08421545],"study_design_scores_gemma":[0.2195152,0.7076316,0.03242629,0.00004292207,0.0006838917,0.0005024752,0.0001057483,0.001050391,0.03512548,0.0001807305,0.002671502,0.00006375724],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980783,0.000655613,0.00009991933,0.00008163715,0.00002198544,0.0001336012,0.0003867222,0.0000423209,0.0004998588],"genre_scores_gemma":[0.9950312,0.0008455413,0.0003829667,0.0002077057,0.00005205683,0.0001928041,0.001246276,0.00001142452,0.00203006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003457905,"threshold_uncertainty_score":0.01156783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04273410199510991,"score_gpt":0.3091101992218122,"score_spread":0.2663760972267022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}