{"id":"W2158946650","doi":"10.1016/j.jalz.2013.08.140","title":"P4‐359: Effects of oral ELND005 (Scyllo‐inositol) on brain scyllo‐inositol and myo‐inositol levels: Spectroscopy results from a phase 2 study in MILD‐TO‐MODERATE Alzheimer's disease","year":2012,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Phytase and its Applications","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"","keywords":"Inositol; Chemistry; Internal medicine; Receptor; Endocrinology; Medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000383078,0.000494078,0.0005672592,0.00008441187,0.0003412874,0.0001249905,0.0004778382,0.0001235965,0.00009256881],"category_scores_gemma":[0.00007049309,0.0002685573,0.000138976,0.0006100349,0.0001019289,0.000440563,0.0002421544,0.0002433595,0.0000925722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000149411,"about_ca_system_score_gemma":0.00002812584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002278453,"about_ca_topic_score_gemma":0.0007592157,"domain_scores_codex":[0.9967276,0.0003434198,0.0007222272,0.0009004345,0.0004956616,0.0008106731],"domain_scores_gemma":[0.9980184,0.0006400686,0.0002624749,0.0003591056,0.00007040796,0.000649587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003735345,0.0153291,0.1096788,0.00001379573,0.005285786,0.00006603105,0.00285697,0.00001340522,0.7566515,0.0004757185,0.02819102,0.07770254],"study_design_scores_gemma":[0.002979764,0.001332728,0.6549149,0.000084719,0.003847662,0.00000105882,0.0002062537,0.0001122514,0.3311311,0.0002073518,0.004539418,0.0006427445],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804192,0.0133542,0.000007626293,0.002920876,0.0002572358,0.002096955,0.0007533204,0.00007617095,0.0001144639],"genre_scores_gemma":[0.9973839,0.00004551983,0.0005354707,0.00106608,0.0003685375,0.0002614942,0.0003250418,0.000009436129,0.00000452192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5452361,"threshold_uncertainty_score":0.9999766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04273410199510991,"score_gpt":0.3091101992218122,"score_spread":0.2663760972267022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}