{"id":"W2158961706","doi":"10.3109/1547691x.2014.934977","title":"Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset","year":2014,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Liver injury; Amodiaquine; CD8; Medicine; Immunology; Internal medicine; Biology; Endocrinology; Malaria; Chloroquine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000752953,0.001773822,0.0009405642,0.002005901,0.0006350562,0.0009231749,0.001104043,0.002248224,0.00358619],"category_scores_gemma":[0.0003066264,0.0007154888,0.00103777,0.0005463705,0.0009458555,0.00128218,0.0006311396,0.00374365,0.001391731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007061788,"about_ca_system_score_gemma":0.0004134807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005666118,"about_ca_topic_score_gemma":0.000963961,"domain_scores_codex":[0.9991844,0.000115632,0.0001203202,0.0002698971,0.0001589866,0.0001506584],"domain_scores_gemma":[0.9993637,0.00006826145,0.0001977923,0.00008529589,0.00006822318,0.0002167396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000862385,0.0009186179,0.0005309416,0.0002269472,0.00004158838,0.0005458939,0.0001192354,0.0002216429,0.9910281,0.001472113,0.0004406728,0.003591799],"study_design_scores_gemma":[0.001016814,0.01120482,0.009036939,0.0002484384,0.0003297462,0.006720269,0.000324598,0.005578666,0.9246569,0.001663361,0.03911231,0.0001070216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9110293,0.006918692,0.05997939,0.002307499,0.0009864511,0.001782252,0.006591297,0.001963818,0.008441326],"genre_scores_gemma":[0.9013191,0.007212629,0.04762481,0.001182781,0.0002463363,0.003491983,0.006944548,0.0004465145,0.0315312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00358619,"threshold_uncertainty_score":0.01199704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1286805316951339,"score_gpt":0.3840023780771183,"score_spread":0.2553218463819844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}