{"id":"W2158973268","doi":"10.4049/jimmunol.177.10.7312","title":"Proteomic Identification of In Vivo Substrates for Matrix Metalloproteinases 2 and 9 Reveals a Mechanism for Resolution of Inflammation","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute","keywords":"Matrix metalloproteinase; MMP9; MMP2; Chemotaxis; Chemokine; Chemistry; Bronchoalveolar lavage; Cell biology; Inflammation; Immunology; Biology; Lung; Biochemistry; Medicine; Downregulation and upregulation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000239667,0.000473636,0.0002645164,0.0002323332,0.000162744,0.000327494,0.0002017659,0.000485361,0.0008162363],"category_scores_gemma":[0.0001819924,0.0001607318,0.0003653148,0.0001255049,0.0001914709,0.0002978687,0.0001488345,0.0006023745,0.0004642505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002270503,"about_ca_system_score_gemma":0.0001666131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002395338,"about_ca_topic_score_gemma":0.0004051593,"domain_scores_codex":[0.9998672,0.0000222478,0.00001357433,0.00003468575,0.00003412808,0.00002813571],"domain_scores_gemma":[0.9998742,0.00001951376,0.00004287677,0.00001541253,0.00001872129,0.00002921567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003639693,0.000005944991,0.000333302,0.00001429163,0.000003654052,0.00004223286,0.000005010465,0.00001003176,0.9992083,0.00002044387,0.0000126825,0.0003076199],"study_design_scores_gemma":[0.00001133181,0.0002719774,0.02307753,0.000008796987,0.00003237729,0.001085258,0.00005532748,0.0008946716,0.9726043,0.0001062835,0.001846279,0.00000594823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875827,0.002570765,0.008520495,0.0002183109,0.00004851323,0.00003298222,0.0004472513,0.00004698483,0.0005319518],"genre_scores_gemma":[0.9835418,0.002075359,0.01153496,0.0001635436,0.00004021331,0.00002938804,0.0008613693,0.00001794736,0.001735551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008162363,"threshold_uncertainty_score":0.002730548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007802904817368692,"score_gpt":0.2418061078663748,"score_spread":0.2340032030490061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}