{"id":"W2158981532","doi":"10.1261/rna.2198203","title":"The effect of a single, temperature-sensitive mutation on global gene expression in <i>Escherichia coli</i>","year":2003,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; U.S. Public Health Service; University of British Columbia; Yale University","keywords":"Biology; DNA microarray; Gene; Genetics; Escherichia coli; RNase P; Gene cluster; Gene expression; Intergenic region; Molecular biology; RNA; Genome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002498799,0.00009225708,0.00009354729,0.000008588075,0.00005008254,0.00001134261,0.00006041077,0.0001041629,0.000001772734],"category_scores_gemma":[0.0001814409,0.00006129453,0.00004636278,0.00007224381,0.00002464304,0.000001539419,0.00001224488,0.0000396808,0.000002983551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001430325,"about_ca_system_score_gemma":0.00001858628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004180259,"about_ca_topic_score_gemma":0.000007666275,"domain_scores_codex":[0.999241,0.000284041,0.0001105679,0.0001541267,0.00009202364,0.0001182332],"domain_scores_gemma":[0.9996963,0.0000342741,0.00005822698,0.0001631084,0.00002345814,0.00002468453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002647646,0.00001927959,0.0000820141,0.00000584947,0.000008117376,0.000004151116,0.00001209116,0.0000439188,0.9979174,0.00007301114,0.00007235734,0.001497095],"study_design_scores_gemma":[0.0003137601,0.0006669174,0.0002937132,0.00003091145,0.0000049557,0.00000393536,0.00001721001,0.000002441791,0.997758,0.00007861431,0.0007617631,0.00006779765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967846,0.0003711919,0.0003040016,0.00002515733,0.0001042583,0.0002164765,0.000006746065,0.000003399047,0.002184222],"genre_scores_gemma":[0.9992799,0.00003354675,0.0004699443,0.00007421029,0.00003288611,0.00001986406,0.00000880102,0.000007551745,0.00007329087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002495358,"threshold_uncertainty_score":0.2499518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005020683770084723,"score_gpt":0.2230685434150486,"score_spread":0.2180478596449639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}