{"id":"W2159166768","doi":"10.1211/jpp.57.11.0015","title":"Attenuation of ciclosporin-induced nephrotoxicity by dietary supplementation of seal oil in Sprague-Dawley rats","year":2005,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Nephrotoxicity; Ciclosporin; Fish oil; Polyunsaturated fatty acid; Sunflower oil; Blood urea nitrogen; Chemistry; Creatinine; Lipid peroxidation; Endocrinology; Internal medicine; Pharmacology; Medicine; Kidney; Fatty acid; Biochemistry; Antioxidant; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004543712,0.0001121059,0.0002452457,0.00009285293,0.00001946981,0.000002770819,0.0001151358,0.00005604366,0.0002197829],"category_scores_gemma":[0.00001549995,0.0001075707,0.00006972047,0.00008979334,0.00006149243,0.00001910326,0.00003692597,0.0001261821,5.81115e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005323294,"about_ca_system_score_gemma":0.00008901311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003716343,"about_ca_topic_score_gemma":0.0000319471,"domain_scores_codex":[0.9988253,0.0001704333,0.0005841154,0.0001294782,0.0001385006,0.0001521571],"domain_scores_gemma":[0.999267,0.00002447944,0.000451323,0.00005770675,0.0001228887,0.00007657283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008992433,0.0002753644,0.01411598,0.00006052651,0.00008433573,0.000002317593,0.0001874162,0.0001411908,0.9492096,0.000004748563,0.005718181,0.02930107],"study_design_scores_gemma":[0.004698587,0.0002631811,0.004813874,0.000007720737,0.00009181414,0.00001447898,0.0000788597,0.0001581607,0.9655551,0.00001153923,0.02421659,0.00009014516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995976,0.002605533,0.00005864667,0.0008130105,0.0002710213,0.0001004759,0.00003713859,9.493185e-7,0.0001372183],"genre_scores_gemma":[0.9942259,0.004547312,0.0003742317,0.0004569054,0.0003017162,0.000004826667,0.00003679513,0.000008097677,0.00004423084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02921092,"threshold_uncertainty_score":0.4386604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01855698243805659,"score_gpt":0.3344829763946591,"score_spread":0.3159259939566025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}