{"id":"W2159174736","doi":"10.1006/jmbi.2000.4470","title":"The crystal structure of dTDP-d-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar typhimurium, the second enzyme in the dTDP-l-rhamnose pathway","year":2001,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Dehydratase; Dehydrogenase; Oxidoreductase; Biochemistry; NAD+ kinase; Enzyme; Stereochemistry; Active site; Cofactor; Biology; Protein structure; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002791026,0.0005489445,0.0006395104,0.0001933322,0.0004579923,0.0009134655,0.0006611229,0.0006182024,0.00181012],"category_scores_gemma":[0.0005528355,0.0002969324,0.0002256359,0.000360523,0.0002697912,0.0004122948,0.0002436739,0.001418088,0.0004328877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001075079,"about_ca_system_score_gemma":0.001167718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01057261,"about_ca_topic_score_gemma":0.01138974,"domain_scores_codex":[0.9999162,0.000009047018,0.000004319457,0.00001646772,0.0000310757,0.00002283627],"domain_scores_gemma":[0.9997919,0.00004688182,0.00003266761,0.000006249956,0.00004927851,0.00007311613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006257904,0.001538148,0.02113989,0.003418702,0.0005510811,0.006400788,0.002262191,0.02129683,0.7137985,0.01185742,0.1284776,0.08300098],"study_design_scores_gemma":[0.004719448,0.003720489,0.1727888,0.0007036573,0.00133244,0.007783844,0.005380299,0.1417489,0.275689,0.004569938,0.381019,0.0005441999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955462,0.01242673,0.004476243,0.003565431,0.0009323611,0.00008210824,0.009066505,0.0006862707,0.01330243],"genre_scores_gemma":[0.9464006,0.008455467,0.00722971,0.0006760021,0.0001428869,0.0000746161,0.02533159,0.0001266851,0.01156245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01057261,"threshold_uncertainty_score":0.02102214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007914601967810575,"score_gpt":0.2599770622439871,"score_spread":0.2520624602761766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}