{"id":"W2159174736","doi":"10.1006/jmbi.2000.4470","title":"The crystal structure of dTDP-d-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar typhimurium, the second enzyme in the dTDP-l-rhamnose pathway","year":2001,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Dehydratase; Dehydrogenase; Oxidoreductase; Biochemistry; NAD+ kinase; Enzyme; Stereochemistry; Active site; Cofactor; Biology; Protein structure; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006585887,0.0002535075,0.0005291927,0.0001190206,0.0001053753,0.00003455851,0.0006303177,0.0001814637,0.0002618544],"category_scores_gemma":[0.0003543351,0.0001138414,0.0003435923,0.0002785106,0.0003298139,0.0000577009,0.00009401111,0.0006391388,0.000006640436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000285998,"about_ca_system_score_gemma":0.000234476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004566144,"about_ca_topic_score_gemma":0.00007993168,"domain_scores_codex":[0.9975644,0.0007364118,0.0007594907,0.000222437,0.000346059,0.0003711709],"domain_scores_gemma":[0.9981024,0.0003257264,0.0005616299,0.0006467492,0.0001949569,0.0001685988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002164849,0.0004235624,0.003344375,0.00002799473,0.0003062934,0.001479595,0.0009636229,0.00002827769,0.9843143,0.0007503249,0.002977195,0.003219569],"study_design_scores_gemma":[0.01544461,0.003452368,0.08293737,0.0002550028,0.001282959,0.004339382,0.007045599,0.0001388904,0.3001967,0.02740681,0.5566899,0.0008104385],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778468,0.01824527,0.0001709178,0.002272413,0.0004643244,0.000284552,0.0002275764,0.000005828505,0.0004822914],"genre_scores_gemma":[0.9953023,0.0007954262,0.000167534,0.003097684,0.0004870403,0.000003561145,0.00004868837,0.00002345195,0.00007437443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6841177,"threshold_uncertainty_score":0.4642317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007914601967810575,"score_gpt":0.2599770622439871,"score_spread":0.2520624602761766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}