{"id":"W2159210115","doi":"10.1074/jbc.m507858200","title":"Protein-tyrosine Phosphatase 1B Deficiency Protects against Fas-induced Hepatic Failure","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation; Cancer Research Society; Pfizer","keywords":"Protein tyrosine phosphatase; Biology; Phosphatase; Signal transduction; Tyrosine phosphorylation; Endocrinology; Cell biology; Internal medicine; Cancer research; Phosphorylation; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001394225,0.0005276129,0.0004307459,0.0004014033,0.0001516423,0.0002733704,0.0002253435,0.0003403576,0.00184532],"category_scores_gemma":[0.0001876675,0.0001793779,0.0001190444,0.0001374739,0.0002822331,0.0002047795,0.0001551987,0.0006324409,0.0004031582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001815742,"about_ca_system_score_gemma":0.0002002222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003302503,"about_ca_topic_score_gemma":0.0003323276,"domain_scores_codex":[0.9999024,0.0000158276,0.000008671337,0.00002281954,0.00002087393,0.00002936482],"domain_scores_gemma":[0.9997941,0.00001819604,0.00005971488,0.00001755716,0.00001835327,0.00009216156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001230791,0.0001559501,0.0003900515,0.00006902822,0.00001700387,0.00009653976,0.00001510528,0.0001302852,0.9924369,0.0001404478,0.0001333765,0.005184526],"study_design_scores_gemma":[0.0004344422,0.004481861,0.01180696,0.00003972727,0.00009103764,0.00099129,0.00006034553,0.001632144,0.9756954,0.0003199239,0.00443197,0.00001480572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937126,0.002844441,0.001597678,0.0001482079,0.00005883695,0.00002108855,0.0003001985,0.0002313239,0.00108558],"genre_scores_gemma":[0.9950991,0.001273412,0.0007091091,0.00004854672,0.00001661699,0.00002636428,0.0004029517,0.000029471,0.002394337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00184532,"threshold_uncertainty_score":0.006173253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01445203736706524,"score_gpt":0.2426480402775243,"score_spread":0.2281960029104591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}