{"id":"W2159211507","doi":"10.1128/jb.183.1.12-27.2001","title":"Mutational Analysis of the OprM Outer Membrane Component of the MexA-MexB-OprM Multidrug Efflux System of <i>Pseudomonas aeruginosa</i>","year":2001,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Cystic Fibrosis Foundation","keywords":"Pseudomonas aeruginosa; Biology; Efflux; Bacterial outer membrane; Component (thermodynamics); Microbiology; Genetics; Mutation; Pseudomonadales; Flagellum; Bacteria; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128869,0.0003145966,0.0001596251,0.0001542757,0.000150813,0.0001487142,0.0002810238,0.0002250169,0.0006866186],"category_scores_gemma":[0.0002475693,0.00009744156,0.0002956283,0.0001698915,0.0001547451,0.0001040562,0.0002047617,0.0004344574,0.0003479898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002901492,"about_ca_system_score_gemma":0.0001844842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001491976,"about_ca_topic_score_gemma":0.001319872,"domain_scores_codex":[0.9999114,0.00002389642,0.00001093587,0.00001152667,0.00002881222,0.00001332047],"domain_scores_gemma":[0.9998416,0.00004945728,0.00004628811,0.00001210498,0.00002036317,0.00003024013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009312774,0.00004909608,0.0006704408,0.00004617673,0.00001054703,0.0003867933,0.00003268998,0.0002987902,0.9970648,0.0001423915,0.00004979258,0.001155297],"study_design_scores_gemma":[0.00003229278,0.0004223201,0.02108646,0.0000264617,0.00006241293,0.001978571,0.0001244106,0.00441148,0.9682326,0.0001138355,0.003487455,0.00002157071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967956,0.000185019,0.001728471,0.00006480799,0.000009955865,0.0000319417,0.000456911,0.00002654664,0.000700677],"genre_scores_gemma":[0.9960052,0.0001716486,0.002236644,0.00003255263,0.000005405281,0.00002046161,0.0008316344,0.00002209745,0.0006743299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001491976,"threshold_uncertainty_score":0.002966583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007197094864567868,"score_gpt":0.2187240046136363,"score_spread":0.2115269097490684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}