{"id":"W2159267978","doi":"10.1186/1475-2859-10-7","title":"Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan","year":2011,"lang":"en","type":"review","venue":"Microbial Cell Factories","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chitosanase; Chitosan; Streptomyces; Biochemistry; Enzyme; Heterologous; Streptomycetaceae; Inducer; Prebiotic; Biology; Chemistry; Microbiology; Gene; Bacteria; Actinomycetales; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001561724,0.0007634615,0.0004303821,0.0002675652,0.0001168967,0.0003890685,0.0003984686,0.0003251239,0.00142535],"category_scores_gemma":[0.000195665,0.0001525495,0.0004636375,0.0003694963,0.0002833561,0.0001417647,0.0002843395,0.000634594,0.0009159179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005436779,"about_ca_system_score_gemma":0.0002539207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001153375,"about_ca_topic_score_gemma":0.0009559232,"domain_scores_codex":[0.9997222,0.00003139618,0.00005312284,0.00006525112,0.00008627986,0.00004170547],"domain_scores_gemma":[0.9996651,0.00006978779,0.0001183758,0.00005188904,0.00002921382,0.00006569287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006898722,0.00003752834,0.00007892063,0.00002352936,0.000003570039,0.00004961699,0.000007291997,0.00004511418,0.9992006,0.00002738553,0.00001616583,0.0004413376],"study_design_scores_gemma":[0.00001684873,0.0001519015,0.001422153,0.000004666982,0.00001046137,0.0001677745,0.00001728869,0.0007091087,0.9965269,0.00001579677,0.0009497401,0.000007296236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9903149,0.0004676205,0.006095938,0.00008424657,0.00009068972,0.00007193947,0.0008836213,0.0003496736,0.001641394],"genre_scores_gemma":[0.986094,0.0003237396,0.006638843,0.00002832296,0.00001191109,0.00005673693,0.002323315,0.0001537087,0.004369485],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00142535,"threshold_uncertainty_score":0.004768312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02809523928252021,"score_gpt":0.2759136932602727,"score_spread":0.2478184539777525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}