{"id":"W2159308963","doi":"10.1073/pnas.1215145110","title":"The human placenta methylome","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Defense","keywords":"DNA methylation; Biology; CpG site; Methylation; Gene; Genetics; Genome; Placenta; Human genome; Differentially methylated regions; Bisulfite sequencing; Promoter; Illumina Methylation Assay; Gene expression; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008361007,0.0000507261,0.00005186193,0.00002730068,0.0002668819,0.00002668416,0.0005251523,0.00005609246,0.000006959531],"category_scores_gemma":[0.0002644928,0.00002752808,0.00004795711,0.0001676341,0.0004741006,0.00001138963,0.00012421,0.00005558402,0.00000129692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005580042,"about_ca_system_score_gemma":0.00001282935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007907251,"about_ca_topic_score_gemma":1.117336e-7,"domain_scores_codex":[0.999158,0.000006188361,0.0001838079,0.0001306399,0.0004250004,0.0000963165],"domain_scores_gemma":[0.9995264,0.00003178239,0.0002085068,0.000008281782,0.0002061164,0.00001893388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000001411174,0.000008307463,0.004210323,0.000004704365,0.000006510412,1.049476e-10,0.00001455371,0.00001650301,0.9852832,0.009303337,0.0007345601,0.0004165717],"study_design_scores_gemma":[0.00006139989,0.00003574713,0.06395306,0.000006333375,0.000002929557,3.391119e-7,0.00005922853,0.00006160836,0.8975356,0.03576985,0.002476732,0.00003714307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886425,0.0004998302,0.000001453473,0.001597902,0.00001375985,0.0001223988,0.000002353547,0.000001687412,0.009118091],"genre_scores_gemma":[0.9987824,0.00009508967,0.0003536563,0.0000893842,0.00007447993,0.00001005224,2.038417e-7,0.000002455241,0.0005922634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08774759,"threshold_uncertainty_score":0.2052667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03215396183773855,"score_gpt":0.3171647692694884,"score_spread":0.2850108074317499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}