{"id":"W2159308963","doi":"10.1073/pnas.1215145110","title":"The human placenta methylome","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Defense","keywords":"DNA methylation; Biology; CpG site; Methylation; Gene; Genetics; Genome; Placenta; Human genome; Differentially methylated regions; Bisulfite sequencing; Promoter; Illumina Methylation Assay; Gene expression; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003263897,0.0002988902,0.0003628088,0.0008043679,0.0004291954,0.0004528202,0.0002822049,0.0003652665,0.01220097],"category_scores_gemma":[0.0009848826,0.0002487634,0.0004000888,0.001184482,0.0001171416,0.0002350403,0.0006812026,0.0003431717,0.005405395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003502539,"about_ca_system_score_gemma":0.0005655718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005629955,"about_ca_topic_score_gemma":0.006371052,"domain_scores_codex":[0.9997883,0.00003917072,0.00001228775,0.00006937149,0.00006185676,0.00002903894],"domain_scores_gemma":[0.9998119,0.00003728471,0.00003299948,0.0000370806,0.0000597503,0.00002095296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001498481,0.00004288314,0.06749591,0.003232751,0.0004381681,0.001403636,0.001286653,0.001442634,0.2435759,0.004145424,0.1858882,0.4895495],"study_design_scores_gemma":[0.00009925671,0.0001763381,0.1689037,0.0004343225,0.0003523593,0.003793941,0.0003418133,0.00199514,0.05145051,0.004092905,0.7682821,0.00007769394],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.2011963,0.0657573,0.05955297,0.005354295,0.000707223,0.0005314991,0.5965366,0.005292392,0.06507144],"genre_scores_gemma":[0.4372114,0.02928397,0.06218051,0.003379503,0.0003223416,0.001011063,0.4288723,0.001005278,0.03673362],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01220097,"threshold_uncertainty_score":0.04081637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03215396183773855,"score_gpt":0.3171647692694884,"score_spread":0.2850108074317499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}