{"id":"W2159370551","doi":"10.1098/rsbl.2012.0614","title":"Mutational effects depend on ploidy level: all else is not equal","year":2012,"lang":"en","type":"article","venue":"Biology Letters","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"University of British Columbia; Killam Trusts","keywords":"Biology; Ploidy; Dominance (genetics); Genetics; Saccharomyces cerevisiae; Adaptation (eye); Allele; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001729544,0.0001569442,0.0001115708,0.00004391013,0.00005530283,0.000006593209,0.0001391912,0.0001954948,0.00003997197],"category_scores_gemma":[0.00007150038,0.0001451072,0.00008104415,0.00003425568,0.00009088979,0.000002733653,0.00006212341,0.00009634768,0.0001857787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000194112,"about_ca_system_score_gemma":0.00002096851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008933474,"about_ca_topic_score_gemma":0.00001009292,"domain_scores_codex":[0.9990188,0.0001227354,0.0001408564,0.000268275,0.00008058862,0.0003687217],"domain_scores_gemma":[0.9995511,0.00004734455,0.00005664358,0.0002156558,0.00002206819,0.0001072266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008697638,0.00008356406,0.008127254,0.000008968529,0.0001015329,0.000002480555,0.00007296129,0.00009846596,0.9752154,0.00111139,0.01330723,0.001783799],"study_design_scores_gemma":[0.003585614,0.001169996,0.1872215,0.00001938206,0.0001110637,0.0001247138,0.00004373392,0.0007553381,0.5122641,0.0002742891,0.2931297,0.001300557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810989,0.0001856797,0.01509951,0.00245058,0.0005571191,0.0001366504,0.00007421296,0.00001791336,0.00037943],"genre_scores_gemma":[0.9628801,0.00001831579,0.001156633,0.03476008,0.0004611096,0.00001923595,0.0004300794,0.00001810103,0.0002563878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4629512,"threshold_uncertainty_score":0.5917298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02819128224551595,"score_gpt":0.2946945744283595,"score_spread":0.2665032921828435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}