{"id":"W2159415787","doi":"","title":"Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.","year":2000,"lang":"en","type":"article","venue":"PubMed","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cytotoxic T cell; CD40; Immunology; Biology; Interleukin 12; CD8; CTL*; IL-2 receptor; Interleukin 21; Immune system; Cancer research; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001767571,0.0003073581,0.000129088,0.0001773267,0.00007966525,0.0003137818,0.0002039387,0.0005362927,0.0009300312],"category_scores_gemma":[0.0001261992,0.0001050619,0.0001870982,0.0001346889,0.0002924175,0.0003191336,0.0001045694,0.0005734636,0.0003043303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002954643,"about_ca_system_score_gemma":0.0002558512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001327009,"about_ca_topic_score_gemma":0.0001617312,"domain_scores_codex":[0.9999489,0.00001390856,0.000003452494,0.000008558599,0.00001161944,0.0000136132],"domain_scores_gemma":[0.9999301,0.0000200474,0.00001924993,0.000006763564,0.000007694133,0.00001615818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006498265,0.0001514278,0.0006166708,0.0002800859,0.0000154083,0.0002590117,0.00002414007,0.0003321929,0.9685699,0.001451622,0.0003135901,0.02733611],"study_design_scores_gemma":[0.0004236528,0.003048692,0.003997662,0.00006014184,0.0001328583,0.002083599,0.00006209801,0.00196683,0.9488298,0.003298938,0.03607158,0.00002413861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8710736,0.08384241,0.03027823,0.004715744,0.000645636,0.000208047,0.0005017988,0.0004282941,0.008306132],"genre_scores_gemma":[0.9463701,0.03249691,0.01450614,0.0006942241,0.0001821374,0.0001164168,0.0004267843,0.0000286293,0.005178734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009300312,"threshold_uncertainty_score":0.003111303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0199782708665502,"score_gpt":0.2423251050910549,"score_spread":0.2223468342245047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}