{"id":"W2159486064","doi":"10.1158/1055-9965.epi-07-2570","title":"Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Gene Polymorphisms and Risk of Reflux Esophagitis, Barrett's Esophagus, and Esophageal Adenocarcinoma","year":2008,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Gastroenterology; Barrett's esophagus; Internal medicine; Esophagus; Reflux esophagitis; Odds ratio; Adenocarcinoma; Medicine; Esophagitis; Population; Esophageal cancer; Reflux; Cancer; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001402533,0.0004089594,0.001041796,0.000403991,0.0003069963,0.000008390734,0.0001042098,0.0003426254,0.0001271265],"category_scores_gemma":[0.000639712,0.0003600521,0.0001706432,0.0003369353,0.001115015,0.0002049956,0.0001534147,0.0003789896,0.000005032171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002048652,"about_ca_system_score_gemma":0.0003057619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002803023,"about_ca_topic_score_gemma":0.00007386845,"domain_scores_codex":[0.9965035,0.0008136401,0.0008054308,0.0009693385,0.0002433938,0.0006646474],"domain_scores_gemma":[0.9976524,0.0006172819,0.0004721438,0.0004676527,0.0001233234,0.0006671978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001125798,0.0001451761,0.9815766,0.0001769623,0.00114489,0.0004306562,0.00007327808,0.000001681404,0.0009793033,0.00008089798,0.0008896723,0.0133751],"study_design_scores_gemma":[0.004170751,0.0008422229,0.9806957,0.0001946162,0.0006821392,0.000938035,0.00003132718,0.0001435408,0.01035833,0.001714067,0.00001371779,0.0002155067],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5642955,0.4343778,0.0001115902,0.0004674545,0.00005387265,0.0005615756,0.00008699893,0.00003273445,0.00001244353],"genre_scores_gemma":[0.9306967,0.06453005,0.003739918,0.0002016665,0.0001389004,0.0002114729,0.0001092248,0.0000425845,0.0003294836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3698478,"threshold_uncertainty_score":0.9998851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04928401380056698,"score_gpt":0.3379232200146683,"score_spread":0.2886392062141014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}