{"id":"W2159538808","doi":"10.1371/journal.pone.0033243","title":"Inhibition of Intestinal Adenoma Formation in APCMin/+ Mice by Riccardin D, a Natural Product Derived from Liverwort Plant Dumortiera hirsuta","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bryophyte Studies and Records","field":"Agricultural and Biological Sciences","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Ministry of Education of the People's Republic of China; National Natural Science Foundation of China; Calgary Laboratory Services","keywords":"Adenoma; Intestinal polyp; Histopathology; Hyperplastic Polyp; Colorectal cancer; Familial adenomatous polyposis; Colorectal Polyp; Pathology; Internal medicine; Immunohistochemistry; Biology; Dysplasia; Adenomatous polyposis coli; Gastroenterology; Molecular biology; Cancer; Medicine; Colonoscopy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009218828,0.0001043037,0.0002133702,0.0000121447,0.00006838018,0.00001096589,0.00007376781,0.00004123943,0.00006018629],"category_scores_gemma":[0.00004932792,0.0000438692,0.0000432717,0.0001792062,0.0000380872,0.0002331464,0.00006391991,0.0001275767,0.00001217347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003787845,"about_ca_system_score_gemma":0.00000222484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006751913,"about_ca_topic_score_gemma":0.0003120441,"domain_scores_codex":[0.9991645,0.00004341111,0.000233376,0.0001483635,0.0001873373,0.0002230733],"domain_scores_gemma":[0.9996795,0.00006450976,0.0001258808,0.0000313757,0.00005320643,0.00004550042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007045941,0.0006000513,0.03417179,0.00002635981,0.00003385542,0.000001563891,0.0004630552,1.120837e-7,0.9602708,0.000003145411,0.0006898223,0.003669011],"study_design_scores_gemma":[0.0002373599,0.0001951435,0.6569771,0.0002539725,0.00004741528,0.000006549682,0.0009918102,0.0001293037,0.3407722,0.00003422607,0.0001572476,0.0001976929],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972963,0.001587124,0.000001127994,0.0003910937,0.0001785608,0.0002282689,0.0001110238,0.0000197373,0.0001867631],"genre_scores_gemma":[0.9985182,0.0001380927,0.0002715678,0.00004345986,0.0006898245,0.00001981592,0.000283246,8.818325e-7,0.00003486436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6228054,"threshold_uncertainty_score":0.1788934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671466805347011,"score_gpt":0.1842506724626941,"score_spread":0.1575360044092239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}