{"id":"W2159566932","doi":"10.1086/373880","title":"Genetic Evidence for Interaction of the 5q31 Cytokine Locus and the CARD15 Gene in Crohn Disease","year":2003,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Thomas Hospital","funders":"European Commission; Wellcome Trust","keywords":"Haplotype; Biology; Genetics; Locus (genetics); Linkage disequilibrium; Transmission disequilibrium test; Odds ratio; Allele; Crohn's disease; Immunology; Disease; Internal medicine; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005655378,0.0001278832,0.0001950399,0.00003719595,0.0001128128,0.0000218162,0.0003923585,0.00002058965,0.00000408969],"category_scores_gemma":[0.0003222356,0.00006871382,0.0001736398,0.00008860193,0.0007800842,0.000004576292,0.00007904013,0.0001205604,2.905545e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000216741,"about_ca_system_score_gemma":0.0001567876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009188732,"about_ca_topic_score_gemma":0.0000234758,"domain_scores_codex":[0.9986843,0.0004335756,0.000411235,0.0001301899,0.0001790321,0.0001617091],"domain_scores_gemma":[0.9986121,0.00008635488,0.0006033417,0.0004437577,0.0001779305,0.00007648253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01406842,0.0003288196,0.2855962,0.000189382,0.0006577873,0.0001487566,0.002098724,0.02446042,0.6585517,0.0008379893,0.001152171,0.0119096],"study_design_scores_gemma":[0.001873221,0.0004065058,0.968198,0.00009115412,0.0002944804,0.0000973888,0.0004865697,0.0001747326,0.02627507,0.001248076,0.0006827972,0.0001720262],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957705,0.003166383,0.0004067029,0.0002056818,0.0001061344,0.0003133249,0.000009479706,9.389295e-7,0.00002087219],"genre_scores_gemma":[0.9985405,0.0006943565,0.0002802595,0.0002605764,0.0001608324,0.00001249823,6.457241e-7,0.00001840226,0.00003189201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6826017,"threshold_uncertainty_score":0.2874253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01581422174243419,"score_gpt":0.2877458713369153,"score_spread":0.2719316495944811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}