{"id":"W2159607262","doi":"10.1016/j.jmb.2012.03.011","title":"APOBEC3B and AID Have Similar Nuclear Import Mechanisms","year":2012,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; APOBEC; Cytidine deaminase; APOBEC3G; Gene; Nuclear transport; Genetics; Cytosine deaminase; DNA; Cytosine; Activation-induced (cytidine) deaminase; Nuclear export signal; Enzyme; Biochemistry; Somatic hypermutation; Cell nucleus; Antibody; Genome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004042957,0.000346406,0.0005080166,0.0004822878,0.0005177149,0.001518752,0.0004380562,0.001010344,0.002490127],"category_scores_gemma":[0.0004614065,0.0002716918,0.0005695637,0.0002724922,0.0005042353,0.0006400995,0.000497699,0.0009595357,0.00131517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001149594,"about_ca_system_score_gemma":0.000377454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002353999,"about_ca_topic_score_gemma":0.002166103,"domain_scores_codex":[0.9997448,0.00005043094,0.00002393618,0.00004337798,0.00007496865,0.00006244535],"domain_scores_gemma":[0.9995747,0.00009625382,0.00005374014,0.00008264161,0.0001129072,0.00007968998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005510809,0.00004238555,0.001481917,0.0001776097,0.00004688737,0.0004211935,0.0001043057,0.000176017,0.9802952,0.005934562,0.0006356205,0.0101332],"study_design_scores_gemma":[0.0001965352,0.0005628001,0.0154948,0.00002883627,0.0001011116,0.007267653,0.0003178193,0.003529825,0.9313188,0.002502549,0.03860154,0.00007779996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9157625,0.01945006,0.03275266,0.001446774,0.0004102726,0.0001758672,0.001469704,0.001270527,0.02726177],"genre_scores_gemma":[0.9709488,0.001827693,0.01419927,0.0002644363,0.00005059984,0.00004991498,0.001207158,0.00006090777,0.01139124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002490127,"threshold_uncertainty_score":0.008340955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007176397731992194,"score_gpt":0.2606758892499329,"score_spread":0.2534994915179407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}