{"id":"W2159631868","doi":"10.1523/jneurosci.3991-13.2014","title":"Prolonged Adenosine A1 Receptor Activation in Hypoxia and Pial Vessel Disruption Focal Cortical Ischemia Facilitates Clathrin-Mediated AMPA Receptor Endocytosis and Long-Lasting Synaptic Inhibition in Rat Hippocampal CA3-CA1 Synapses: Differential Regulation of GluA2 and GluA1 Subunits by p38 MAPK and JNK","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Saskatchewan Health Research Foundation","keywords":"AMPA receptor; Hippocampal formation; Cell biology; Postsynaptic potential; Glutamate receptor; Adenosine; Chemistry; Biology; Neuroscience; Receptor; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154854,0.0003806863,0.0004675056,0.000139614,0.0001955164,0.000229778,0.0002282038,0.0002325912,0.001082449],"category_scores_gemma":[0.00008937874,0.0001917393,0.0003922496,0.0001762707,0.0002229899,0.0002450651,0.0002085209,0.0006021273,0.0001961164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004688943,"about_ca_system_score_gemma":0.0002594198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002063679,"about_ca_topic_score_gemma":0.00299901,"domain_scores_codex":[0.9998486,0.00001059041,0.00001238704,0.00003131238,0.00002759537,0.00006943875],"domain_scores_gemma":[0.9999516,0.000002907293,0.00001677912,0.00000526602,0.000004613646,0.00001880538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009367039,0.00005315724,0.0002786103,0.00007131007,0.00002095501,0.0001695135,0.00004952744,0.00006461549,0.9968154,0.0001347165,0.000101561,0.001303952],"study_design_scores_gemma":[0.0001073575,0.001220464,0.03695774,0.00001661125,0.0001066696,0.0006004448,0.0001030836,0.001733487,0.9569659,0.0001146209,0.002057914,0.00001562624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960355,0.001833161,0.0009098802,0.00008815568,0.00003562678,0.00002589151,0.0002584618,0.00003383898,0.0007795223],"genre_scores_gemma":[0.9959001,0.001110389,0.0007040667,0.00005229967,0.0000242229,0.0001415807,0.0004702497,0.000006326326,0.001590814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002063679,"threshold_uncertainty_score":0.004103363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02841199422343834,"score_gpt":0.2864060054115728,"score_spread":0.2579940111881345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}