{"id":"W2159692922","doi":"10.1038/srep08278","title":"Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Alberta Health Services","funders":"National Institute of Neurological Disorders and Stroke; National Brain Tumor Society; U.S. Public Health Service; National Cancer Institute; National Institutes of Health; National Human Genome Research Institute; American Brain Tumor Association","keywords":"Sanger sequencing; Genetics; Glioma; Biology; Genetic linkage; Locus (genetics); Chromosome; Candidate gene; Linkage (software); Gene; Computational biology; DNA sequencing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006248868,0.0003647105,0.0003824882,0.002011121,0.0005137133,0.0004943096,0.000319189,0.0003373498,0.001935856],"category_scores_gemma":[0.001589736,0.0001204211,0.0003680771,0.001517613,0.0001950814,0.00006736934,0.0004969226,0.0002397483,0.0004046083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002667837,"about_ca_system_score_gemma":0.0006252531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005983553,"about_ca_topic_score_gemma":0.009280158,"domain_scores_codex":[0.9995995,0.00006764181,0.000028285,0.00010924,0.0001241671,0.00007119072],"domain_scores_gemma":[0.9995701,0.0001249934,0.00009631122,0.00003814765,0.00007849756,0.00009199463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001891587,0.000147818,0.7342774,0.0002586004,0.0008412346,0.02029582,0.001110293,0.001958012,0.1596845,0.001284214,0.005500366,0.07275017],"study_design_scores_gemma":[0.0001722372,0.0003629653,0.9225139,0.0001173369,0.0008665674,0.01778319,0.0005537384,0.004372993,0.02964903,0.001177999,0.02238053,0.00004945438],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947389,0.0006484052,0.001737366,0.0000983853,0.00001747489,0.00002815616,0.00192981,0.00005632249,0.0007453429],"genre_scores_gemma":[0.9877301,0.0007861839,0.004208037,0.0001221541,0.00002607766,0.00005690184,0.005936468,0.00005248185,0.001081689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005983553,"threshold_uncertainty_score":0.01189744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02644549259325537,"score_gpt":0.2662481703698121,"score_spread":0.2398026777765568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}