{"id":"W2159794260","doi":"10.1158/0008-5472.can-06-4221","title":"Hypoxia Enhances Metastatic Efficiency in HT1080 Fibrosarcoma Cells by Increasing Cell Survival in Lungs, Not Cell Adhesion and Invasion","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"HT1080; Fibrosarcoma; Extravasation; Hypoxia (environmental); Apoptosis; Metastasis; Cancer research; Biology; Cell; Tirapazamine; Cell culture; Pathology; Immunology; Chemistry; Medicine; In vitro; Cytotoxicity; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006692298,0.0001621968,0.0001396967,0.00008210616,0.00006587985,0.0001003229,0.00004778698,0.0001041466,0.0009022605],"category_scores_gemma":[0.00006107358,0.00006873062,0.0001075884,0.00004451071,0.00007409552,0.0001154853,0.00007362714,0.0001763447,0.0001860091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001518196,"about_ca_system_score_gemma":0.00009799188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009777453,"about_ca_topic_score_gemma":0.001889814,"domain_scores_codex":[0.9999574,0.00001217762,0.000002433949,0.000005846161,0.00001138361,0.00001082449],"domain_scores_gemma":[0.9999597,0.00001077917,0.00001021208,0.000004007237,0.000005045248,0.00001023817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003692332,0.00000836422,0.0001232932,0.00001085361,0.000001245733,0.00002287893,0.000005473365,0.00001687965,0.9991468,0.00001675835,0.00001510249,0.0005954857],"study_design_scores_gemma":[0.0000146397,0.0009525279,0.01908226,0.000006321403,0.00001290593,0.0004513102,0.00002893701,0.0006401477,0.9770342,0.00003304871,0.001740507,0.000003255311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947949,0.002534884,0.0009416304,0.00007601446,0.0000114329,0.00001301109,0.0001129698,0.00002315738,0.00149213],"genre_scores_gemma":[0.9946178,0.00158009,0.001067654,0.00003938137,0.000009914596,0.0000139966,0.0001848377,0.000007683416,0.002478609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009777453,"threshold_uncertainty_score":0.003018379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02991943713169778,"score_gpt":0.3328820491839109,"score_spread":0.3029626120522131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}