{"id":"W2159794319","doi":"10.1158/0008-5472.can-05-0471","title":"Amplification and Overexpression of the <i>KIT</i> Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Testicular diseases and treatments","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Seminoma; Biology; Cancer research; Gene duplication; Exon; PDGFRA; Gene; Tumor progression; Proto-Oncogene Proteins c-kit; Germ cell; Carcinogenesis; Germ cell tumors; Molecular biology; Genetics; Stem cell factor; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001138436,0.000128351,0.0001764421,0.0007657599,0.000156483,0.0002062138,0.0000903641,0.0001549527,0.0009962051],"category_scores_gemma":[0.0006807513,0.0001484238,0.00009929787,0.0003549788,0.0002453461,0.0001420681,0.0001295845,0.0002005616,0.0001489553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008809526,"about_ca_system_score_gemma":0.0001076083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007532767,"about_ca_topic_score_gemma":0.001130336,"domain_scores_codex":[0.9998999,0.00001731869,0.00001172099,0.00001991421,0.00002970312,0.00002155592],"domain_scores_gemma":[0.999428,0.0001141963,0.0002762832,0.00001827349,0.00005608527,0.0001071306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002176218,0.0000185518,0.9659571,0.00002439431,0.00001960825,0.002516599,0.0002130008,0.00005668628,0.02473546,0.00004754069,0.0001132217,0.006080217],"study_design_scores_gemma":[0.000006087163,0.0001564974,0.9815063,0.0000041121,0.00001999661,0.01443267,0.0001391379,0.0001402997,0.003195435,0.00004291377,0.0003536562,0.000002874089],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997031,0.00009376081,0.00007036519,0.000007219378,6.469548e-7,0.000001351947,0.00002170844,0.000003647764,0.00009821954],"genre_scores_gemma":[0.9996114,0.00009070975,0.0001143806,0.000004674245,0.00000449294,0.000002284969,0.00007635089,0.000001715076,0.00009394016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009962051,"threshold_uncertainty_score":0.003332615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02661734444610617,"score_gpt":0.3439220614727944,"score_spread":0.3173047170266882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}