{"id":"W2159862107","doi":"10.1200/jco.2011.41.0985","title":"Concurrent Expression of MYC and BCL2 in Diffuse Large B-Cell Lymphoma Treated With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":973,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation; Michael Smith Health Research BC","keywords":"Vincristine; Medicine; Chromosomal translocation; International Prognostic Index; Immunohistochemistry; Rituximab; Lymphoma; Cyclophosphamide; Prednisone; Diffuse large B-cell lymphoma; Cancer research; CHOP; Internal medicine; Oncology; Cohort; Immunophenotyping; Pathology; Chemotherapy; Immunology; Flow cytometry; Biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003256015,0.000195099,0.0003083137,0.0003956283,0.0003016047,0.0003654283,0.0002271921,0.0002402114,0.0004938163],"category_scores_gemma":[0.000962871,0.0002248775,0.0002295104,0.000328892,0.000301887,0.000209397,0.0002914698,0.0003613723,0.0001178452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003912305,"about_ca_system_score_gemma":0.0002644937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001545683,"about_ca_topic_score_gemma":0.002515558,"domain_scores_codex":[0.9997543,0.00005633133,0.00002154824,0.0000675976,0.00005975273,0.00004057224],"domain_scores_gemma":[0.9995987,0.0001034679,0.0001157049,0.00003023004,0.00003320643,0.0001187298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006296638,0.00006051567,0.9933761,0.0000107599,0.00004777496,0.0004127576,0.00006860431,0.00005955287,0.002848839,0.000008517835,0.00005538574,0.00242157],"study_design_scores_gemma":[0.00006899345,0.0004780821,0.995021,0.000006078215,0.00007434381,0.002740208,0.0001195746,0.0004889105,0.000747848,0.00001875044,0.0002313312,0.000004909841],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997637,0.0001159463,0.00002752206,0.00000712837,0.000001914386,0.000002270204,0.00002106458,0.000001391704,0.00005906998],"genre_scores_gemma":[0.9997892,0.0000456729,0.00003175958,0.00000975541,0.00000420916,0.000002399913,0.00008982278,6.09031e-7,0.00002670872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001545683,"threshold_uncertainty_score":0.003073335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04353290157636887,"score_gpt":0.3813756691600561,"score_spread":0.3378427675836872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}