{"id":"W2159872876","doi":"10.1182/blood-2002-10-3233","title":"Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Homing (biology); Biology; Cell biology; Stem cell; Anaphylatoxin; Haematopoiesis; Progenitor cell; Bone marrow; CD34; Stromal cell; Immunology; Complement system; Cancer research; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220789,0.0003292029,0.0001538397,0.0002346445,0.0001371455,0.000244339,0.0001269199,0.0002268789,0.003997875],"category_scores_gemma":[0.00009017017,0.00008150471,0.0001661397,0.000143363,0.0001636852,0.0001036944,0.000199617,0.0003960298,0.001187272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853038,"about_ca_system_score_gemma":0.0002303237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008123573,"about_ca_topic_score_gemma":0.0006612291,"domain_scores_codex":[0.9998832,0.00001643645,0.000009096882,0.00002134578,0.0000399042,0.00003002491],"domain_scores_gemma":[0.9999316,0.000007381006,0.00001457421,0.000008663134,0.00001122833,0.00002664591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006026953,0.00001204739,0.0003173651,0.00001610447,0.000003185559,0.00006003576,0.000009652896,0.00002218268,0.9976962,0.0001403633,0.00007326562,0.001589186],"study_design_scores_gemma":[0.00003570758,0.0003259807,0.02105103,0.00001347453,0.00003038578,0.001845648,0.00005790857,0.00095769,0.9656931,0.0002117181,0.009770515,0.000006808713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896815,0.002125864,0.004139717,0.0001457232,0.00002723127,0.00004683353,0.0009574087,0.0001450862,0.002730501],"genre_scores_gemma":[0.9917414,0.0007686863,0.002022411,0.00005404503,0.00001089538,0.00004209521,0.001120827,0.0000195518,0.004220139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003997875,"threshold_uncertainty_score":0.01337421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357763744282852,"score_gpt":0.2207275343598178,"score_spread":0.2071498969169893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}