{"id":"W2159872876","doi":"10.1182/blood-2002-10-3233","title":"Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Homing (biology); Biology; Cell biology; Stem cell; Anaphylatoxin; Haematopoiesis; Progenitor cell; Bone marrow; CD34; Stromal cell; Immunology; Complement system; Cancer research; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002698254,0.0002699498,0.000333614,0.0001128109,0.0002898181,0.00003593227,0.0001768458,0.0001786447,0.001254867],"category_scores_gemma":[0.00006647524,0.0002435601,0.0001259119,0.0001382139,0.00009399622,0.00008472408,0.00006284038,0.0001042184,0.0002603883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001793603,"about_ca_system_score_gemma":0.0000777274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005042454,"about_ca_topic_score_gemma":0.000003059814,"domain_scores_codex":[0.9983253,0.0002910801,0.0004218393,0.0004832224,0.00005799302,0.0004205054],"domain_scores_gemma":[0.9990501,0.0003293808,0.0001428094,0.0003146746,0.00008894025,0.00007412166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003729222,0.0004001606,0.002389344,0.00007483181,0.0003467192,7.929149e-7,0.0005144058,3.095809e-7,0.9160966,0.0001028094,0.07956556,0.0001355083],"study_design_scores_gemma":[0.002607197,0.0002891541,0.000368293,0.00005518614,0.00008261536,0.00002187763,0.0006302555,3.063103e-7,0.8835772,0.00003629955,0.1120684,0.0002631815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883018,0.008110243,0.0001214824,0.0001428087,0.0006940443,0.0009232705,0.001507495,0.00009270428,0.0001062155],"genre_scores_gemma":[0.9944928,0.00003948086,0.000171501,0.000150947,0.00003517317,0.0003891287,0.0001276318,0.00003185014,0.004561542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03251942,"threshold_uncertainty_score":0.9996581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357763744282852,"score_gpt":0.2207275343598178,"score_spread":0.2071498969169893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}