{"id":"W2159943759","doi":"10.1001/jama.283.4.492","title":"Nucleoside Analogs Plus Ritonavir in Stable Antiretroviral Therapy–Experienced HIV-Infected Children<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>","year":2000,"lang":"en","type":"article","venue":"JAMA","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, University of North Carolina at Chapel Hill; National Institute of Allergy and Infectious Diseases; National Institute of Child Health and Human Development; Abbott Laboratories; University of California, San Diego; University of North Carolina at Chapel Hill; National Institutes of Health; Bristol-Myers Squibb; York University; University of Pittsburgh; University of Minnesota; Harvard University; Bunning Food Allergy Institute, Ann and Robert H. Lurie Children's Hospital of Chicago; Children's Hospital of Philadelphia","keywords":"Medicine; Ritonavir; Regimen; Stavudine; Lamivudine; Zidovudine; Indinavir; Internal medicine; Didanosine; Randomized controlled trial; Protease inhibitor (pharmacology); Clinical trial; Nelfinavir; Viral load; Gastroenterology; Immunology; Viral disease; Antiretroviral therapy; Human immunodeficiency virus (HIV); Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001502245,0.0009936847,0.00237547,0.0003614225,0.0003325209,0.0007489182,0.0007644956,0.001183403,0.003710181],"category_scores_gemma":[0.001934821,0.0005186608,0.00160748,0.0004806386,0.0008485246,0.0006317424,0.0002671984,0.002242835,0.0003171071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007413169,"about_ca_system_score_gemma":0.001261633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001635585,"about_ca_topic_score_gemma":0.003636496,"domain_scores_codex":[0.9991869,0.0005607193,0.00005498156,0.00006904577,0.00005038472,0.00007789469],"domain_scores_gemma":[0.9988973,0.000327582,0.0004008898,0.00005082912,0.00005307552,0.0002702321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9729048,0.004532762,0.002267623,0.001918284,0.001404216,0.0001094741,0.00007577689,0.0003232058,0.001658177,0.000124726,0.0007243681,0.01395667],"study_design_scores_gemma":[0.954321,0.04200277,0.002279813,0.00005869864,0.0004431024,0.00004700461,0.00002410028,0.0001818078,0.0002460105,0.00003727933,0.0003520367,0.000006531488],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885245,0.006835391,0.0002687215,0.0003836245,0.0002381636,0.002175803,0.0006571328,0.00004546533,0.0008712244],"genre_scores_gemma":[0.9858121,0.005954396,0.001393628,0.0007701024,0.0003982385,0.004130861,0.0006447469,0.000009833484,0.0008861069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003710181,"threshold_uncertainty_score":0.01241177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007770306467116419,"score_gpt":0.2457569508733633,"score_spread":0.2379866444062469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}