{"id":"W2159953413","doi":"10.1021/jo061279q","title":"A Novel Approach to Oligonucleotide Synthesis Using an Imidazolium Ion Tag as a Soluble Support","year":2006,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oligonucleotide; Oligonucleotide synthesis; Combinatorial chemistry; Cleavage (geology); Ionic liquid; Chemistry; Solid-phase synthesis; Base (topology); Ion; Chromatography; Materials science; Organic chemistry; DNA; Biochemistry; Catalysis; Peptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002580224,0.0006701321,0.0007266824,0.0003713474,0.0004108826,0.0005949773,0.0008789795,0.0007981159,0.001100822],"category_scores_gemma":[0.0002962199,0.0005385536,0.0004923926,0.0003011226,0.000331478,0.0005152244,0.0005513878,0.001756613,0.001545596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003840533,"about_ca_system_score_gemma":0.0006153264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002464179,"about_ca_topic_score_gemma":0.000544866,"domain_scores_codex":[0.9996574,0.00003272014,0.00004063731,0.0001047293,0.000125583,0.00003890982],"domain_scores_gemma":[0.9998112,0.00003894235,0.00004264013,0.00003020482,0.00003912241,0.00003784991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001423442,0.00002424327,0.0000236099,0.00007207163,0.00000438987,0.00008133923,0.00001450789,0.00005884717,0.9937345,0.0003465055,0.00008435379,0.005541435],"study_design_scores_gemma":[0.00002549303,0.0003316407,0.0002000821,0.00001016358,0.00002459382,0.001207545,0.00001126677,0.00102044,0.9743667,0.0003888541,0.0223885,0.00002475978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1790375,0.007464559,0.8025085,0.0007237165,0.001130986,0.0006068241,0.0005046524,0.002307474,0.005715844],"genre_scores_gemma":[0.2227672,0.008281499,0.7551864,0.0004982115,0.0003370653,0.0007647162,0.001223646,0.0003154328,0.01062593],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001100822,"threshold_uncertainty_score":0.003682554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01202704963949607,"score_gpt":0.2294036554630854,"score_spread":0.2173766058235893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}