{"id":"W2159956768","doi":"10.1021/bi0497300","title":"T7 RNA Polymerase Mediates Fast Promoter-Independent Extension of Unstable Nucleic Acid Complexes","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Base pair; Nucleotide; Polymerase; RNA; Transcription (linguistics); Molecular biology; Oligonucleotide; DNA; Biology; Nucleic acid; T7 RNA polymerase; RNA polymerase; Biochemistry; Chemistry; Gene; Bacteriophage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001578975,0.0002440421,0.0002364505,0.0000303117,0.00008550167,0.00002160944,0.000309227,0.0002705862,0.0001136172],"category_scores_gemma":[0.00007632878,0.000230225,0.0001382417,0.00008103775,0.0001133019,0.000005263757,0.0001536419,0.00008549592,0.00001758346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002471496,"about_ca_system_score_gemma":0.0001373131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004451608,"about_ca_topic_score_gemma":0.000004481229,"domain_scores_codex":[0.9986184,0.00002730116,0.0003065468,0.0004784305,0.0002526716,0.0003166567],"domain_scores_gemma":[0.9989917,0.000006651456,0.0001717259,0.0005911262,0.00009289127,0.0001459193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008385337,0.0001508239,0.000076693,0.00008300009,0.00004173088,0.000007815479,0.00002995123,0.000006578116,0.9966357,0.0000322377,0.0001387404,0.002712844],"study_design_scores_gemma":[0.000666731,0.0001666782,0.0001173357,0.00008143195,0.00002245575,0.00002903207,0.0001028639,0.000004110108,0.9978383,0.00025676,0.000451167,0.0002631675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954156,0.002469985,0.0009183619,0.0001480189,0.0001149502,0.0001793008,0.00006783455,0.00002562773,0.0006602809],"genre_scores_gemma":[0.9971411,0.0001580325,0.001767044,0.00009157067,0.0001964443,0.00002143395,0.0001546263,0.00003621544,0.0004335116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002449677,"threshold_uncertainty_score":0.9388303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009426641811945788,"score_gpt":0.2253056004459429,"score_spread":0.2158789586339971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}