{"id":"W2159956768","doi":"10.1021/bi0497300","title":"T7 RNA Polymerase Mediates Fast Promoter-Independent Extension of Unstable Nucleic Acid Complexes","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Base pair; Nucleotide; Polymerase; RNA; Transcription (linguistics); Molecular biology; Oligonucleotide; DNA; Biology; Nucleic acid; T7 RNA polymerase; RNA polymerase; Biochemistry; Chemistry; Gene; Bacteriophage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005800649,0.000605307,0.0004502686,0.0002502073,0.0001784203,0.0006185413,0.0004446327,0.000307497,0.0004006744],"category_scores_gemma":[0.000868936,0.0002944446,0.0003365019,0.0001504182,0.0004567043,0.0005085914,0.000641003,0.0006374822,0.0005598672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002549512,"about_ca_system_score_gemma":0.0001692793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519729,"about_ca_topic_score_gemma":0.00021848,"domain_scores_codex":[0.9995677,0.0001091373,0.00002929754,0.0001043699,0.0001208131,0.00006867274],"domain_scores_gemma":[0.9993626,0.0002692161,0.0001177662,0.00009352263,0.00007178901,0.00008491401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004119751,0.00001027382,0.0001439398,0.00003744528,0.000004860781,0.0000467011,0.00002594939,0.0001007197,0.9976119,0.0002707456,0.00001678506,0.001689545],"study_design_scores_gemma":[0.000005692397,0.0001027987,0.0004351135,0.000005566603,0.000007448426,0.0001243539,0.00001134764,0.001861262,0.9963776,0.0001507902,0.0009130952,0.0000049205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9515169,0.003094067,0.0436324,0.00003685915,0.00003012431,0.00006281121,0.00007904059,0.0002330248,0.001314807],"genre_scores_gemma":[0.9855194,0.001107062,0.01150126,0.00001788396,0.000019758,0.00004454623,0.000281723,0.00008612304,0.001422216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006185413,"threshold_uncertainty_score":0.003067672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009426641811945788,"score_gpt":0.2253056004459429,"score_spread":0.2158789586339971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}