{"id":"W2159961666","doi":"10.21236/ada429094","title":"Nuclear Receptor Interactions in Breast Cancer: The Role of Kinase Signaling Pathways","year":2004,"lang":"en","type":"report","venue":"","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Medical Research and Materiel Command","keywords":"MAPK/ERK pathway; Apoptosis; Retinoic acid; Cancer research; Downregulation and upregulation; Estrogen receptor; p38 mitogen-activated protein kinases; Signal transduction; Cell growth; Kinase; Protein kinase C; Cell biology; Chemistry; Biology; Internal medicine; Cell culture; Cancer; Breast cancer; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001880929,0.000464646,0.0002586243,0.0002811385,0.000322383,0.0005430536,0.0002443428,0.0003561125,0.003027048],"category_scores_gemma":[0.0001174437,0.0001572601,0.0001781595,0.0002995229,0.0002749132,0.0006032389,0.000256453,0.0005992885,0.001465493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007178293,"about_ca_system_score_gemma":0.0003492804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006548514,"about_ca_topic_score_gemma":0.001362364,"domain_scores_codex":[0.9998854,0.0000208777,0.000008383849,0.00002335869,0.00003519024,0.00002684818],"domain_scores_gemma":[0.9999467,0.000009102441,0.0000135645,0.000005852832,0.00001042056,0.00001441992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0008566526,0.0001371805,0.00191374,0.001524353,0.00004831968,0.001240728,0.0001872641,0.0004338661,0.8808876,0.005876653,0.003258566,0.103635],"study_design_scores_gemma":[0.0001095193,0.00058734,0.02191809,0.0002394851,0.0001704153,0.01284577,0.0003627324,0.0007210234,0.6297314,0.003568964,0.3297024,0.00004288579],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.2837158,0.6739991,0.007130522,0.005304495,0.0004925595,0.00006928117,0.0004816268,0.0002402669,0.02856636],"genre_scores_gemma":[0.6152765,0.3499332,0.005249399,0.0003810495,0.0004215978,0.0000616153,0.0005898223,0.00003455807,0.02805234],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003027048,"threshold_uncertainty_score":0.01012647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294128566490812,"score_gpt":0.2611854684726341,"score_spread":0.2482441828077259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}