{"id":"W2160033413","doi":"10.1074/jbc.m111.310664","title":"Insights into O-Linked N-Acetylglucosamine ([0-9]O-GlcNAc) Processing and Dynamics through Kinetic Analysis of O-GlcNAc Transferase and O-GlcNAcase Activity on Protein Substrates","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Enzyme; Biochemistry; Biology; Transferase; In vitro; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001655855,0.0003673694,0.0002090349,0.0001550799,0.00007799715,0.0003886783,0.0002037238,0.000255501,0.0003000649],"category_scores_gemma":[0.000260971,0.0001832755,0.0002826761,0.0002008982,0.0002009896,0.0003908093,0.0001283393,0.000413319,0.0001960189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002716983,"about_ca_system_score_gemma":0.0001311398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007857622,"about_ca_topic_score_gemma":0.0005835426,"domain_scores_codex":[0.999918,0.00001130076,0.000007264376,0.00002234365,0.00002417656,0.00001687186],"domain_scores_gemma":[0.9998966,0.00002292148,0.00003255657,0.00001063412,0.00001834375,0.00001887366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008418987,0.00001550162,0.001105336,0.00002945568,0.000009078382,0.00003131524,0.00001848572,0.0006047859,0.9968892,0.0001230312,0.00001250161,0.001077214],"study_design_scores_gemma":[0.000004986035,0.0001493642,0.01309596,0.000005380823,0.0000147073,0.0001927503,0.00005088424,0.01146051,0.974067,0.0001843412,0.0007590875,0.00001492002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942896,0.0005233123,0.004553085,0.00002277561,0.000003224249,0.00000980035,0.000180383,0.00002349236,0.0003943141],"genre_scores_gemma":[0.9935102,0.0008503879,0.004534511,0.000019899,0.000002778796,0.00001617366,0.0005387521,0.00002467878,0.0005026924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007857622,"threshold_uncertainty_score":0.001971304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545277970225828,"score_gpt":0.2959932056414553,"score_spread":0.270540425939197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}