{"id":"W2160033413","doi":"10.1074/jbc.m111.310664","title":"Insights into O-Linked N-Acetylglucosamine ([0-9]O-GlcNAc) Processing and Dynamics through Kinetic Analysis of O-GlcNAc Transferase and O-GlcNAcase Activity on Protein Substrates","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Enzyme; Biochemistry; Biology; Transferase; In vitro; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000282299,0.0002314946,0.0004639261,0.00008250301,0.00008361717,0.00002913333,0.0001530134,0.0003435371,0.00002632557],"category_scores_gemma":[0.0002505675,0.0001629101,0.0001617013,0.0003316789,0.0003061288,0.00002581112,0.00006813712,0.0003192399,3.260897e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000374217,"about_ca_system_score_gemma":0.00006364354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001507773,"about_ca_topic_score_gemma":0.00001217442,"domain_scores_codex":[0.9986783,0.000101035,0.0004437935,0.0002702387,0.0002433838,0.0002632843],"domain_scores_gemma":[0.9990568,0.00004631332,0.000287996,0.000181777,0.0002117011,0.0002153781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006626507,0.0002852062,0.004999649,0.0001422332,0.0002248291,0.000009559488,0.00007951542,0.00002337346,0.9899938,0.00006083543,0.000004308019,0.003514104],"study_design_scores_gemma":[0.0008509468,0.0006997446,0.02144315,0.00005273751,0.0001341817,0.00004263692,0.0001655785,0.0006354823,0.975267,0.0001535465,0.000339038,0.0002159732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958179,0.002362795,0.001206435,0.0001864358,0.00001462382,0.0001718258,0.00001562078,0.000005305616,0.000219067],"genre_scores_gemma":[0.9982532,0.0005915313,0.0008736537,0.00004265735,0.0001274619,0.000009598499,0.00005195421,0.00001152966,0.00003837754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01644351,"threshold_uncertainty_score":0.6643282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545277970225828,"score_gpt":0.2959932056414553,"score_spread":0.270540425939197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}