{"id":"W2160043121","doi":"10.1152/ajpgi.00227.2002","title":"Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"TRPC; TRPC5; Thapsigargin; TRPC3; Transient receptor potential channel; Endocrinology; Internal medicine; TRPC1; TRPV; Chemistry; Fura-2; Endoplasmic reticulum; Cell biology; Biology; Receptor; Biochemistry; Medicine; TRPV1; Cytosol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001507389,0.0001232845,0.0002195105,0.0002287696,0.0001075347,0.0002993371,0.00005295536,0.0002266175,0.001798344],"category_scores_gemma":[0.0003278295,0.0001274574,0.0002110615,0.0002066539,0.0002000917,0.0001829797,0.0001520648,0.000287108,0.0004086354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604678,"about_ca_system_score_gemma":0.0001004953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005133746,"about_ca_topic_score_gemma":0.0003868376,"domain_scores_codex":[0.9998791,0.00002324623,0.000009599536,0.00003002467,0.00003373492,0.00002425342],"domain_scores_gemma":[0.9998659,0.0000352495,0.00002636677,0.0000187251,0.00003215922,0.00002161565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002281343,0.000009689484,0.001372514,0.00002988875,0.000003888049,0.0001506854,0.00006223869,0.00001688785,0.997039,0.00002735961,0.00003939194,0.001020366],"study_design_scores_gemma":[0.00008369883,0.0011811,0.1911386,0.00002759605,0.00007478226,0.002874949,0.0004096427,0.001444468,0.7970849,0.0001119155,0.005551906,0.00001653748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972672,0.0008930267,0.000781386,0.00005890956,0.00001077918,0.00001387759,0.0002528193,0.00002911438,0.0006928155],"genre_scores_gemma":[0.996745,0.0004914026,0.0007865006,0.00006381753,0.00001388644,0.00003619506,0.0005596553,0.000008985378,0.001294502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001798344,"threshold_uncertainty_score":0.006016016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357023674158504,"score_gpt":0.2599202688841706,"score_spread":0.2363500321425856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}