{"id":"W2160043121","doi":"10.1152/ajpgi.00227.2002","title":"Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"TRPC; TRPC5; Thapsigargin; TRPC3; Transient receptor potential channel; Endocrinology; Internal medicine; TRPC1; TRPV; Chemistry; Fura-2; Endoplasmic reticulum; Cell biology; Biology; Receptor; Biochemistry; Medicine; TRPV1; Cytosol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000173165,0.0002733345,0.0006004932,0.0001908847,0.0002055423,0.00001149542,0.0001756078,0.000049582,0.00005514891],"category_scores_gemma":[0.0002344487,0.0002033882,0.00009527585,0.0002033428,0.001514964,0.0001526521,0.00007730039,0.0004899926,0.000002628038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002947364,"about_ca_system_score_gemma":0.00004496823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007216935,"about_ca_topic_score_gemma":0.000003319625,"domain_scores_codex":[0.9978316,0.0007146322,0.0004290921,0.0004515058,0.0001220384,0.0004510673],"domain_scores_gemma":[0.9986642,0.0003920993,0.0005746236,0.00009830036,0.0000918235,0.000178931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001962427,0.0001634531,0.000063593,0.00001712098,0.0000050266,0.00001888873,0.001025085,0.0001407162,0.9969805,0.0002906257,0.00002962378,0.001069057],"study_design_scores_gemma":[0.001203541,0.004062589,0.05573854,0.0001978123,0.00001549472,0.0005166227,0.003031614,0.0001212098,0.9320267,0.002739239,0.00005705272,0.0002896014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988659,0.0001267991,0.000577702,0.00006278701,0.0001472255,0.00009923856,0.000007860392,0.00001130242,0.0001012009],"genre_scores_gemma":[0.9980118,0.0001989822,0.001357801,0.0002011954,0.0001755171,0.000006551198,0.000001621639,0.00001811875,0.00002835887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06495388,"threshold_uncertainty_score":0.829393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357023674158504,"score_gpt":0.2599202688841706,"score_spread":0.2363500321425856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}