{"id":"W2160074417","doi":"10.1091/mbc.e07-04-0394","title":"Distinct Functions for Arf Guanine Nucleotide Exchange Factors at the Golgi Complex: GBF1 and BIGs Are Required for Assembly and Maintenance of the Golgi Stack and<i>trans</i>-Golgi Network, Respectively","year":2007,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Universität Zürich; Fondation pour la Recherche Médicale; University of Alberta","keywords":"COPI; Golgi apparatus; Guanine nucleotide exchange factor; COPII; Biology; Cell biology; Golgi membrane; Endoplasmic reticulum; Brefeldin A; ADP ribosylation factor; Signal transducing adaptor protein; Gene knockdown; GTPase; Secretory pathway; Biochemistry; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001856423,0.0006228345,0.0002807351,0.0002783455,0.0002042586,0.0005465992,0.0002188441,0.0003143705,0.0007515502],"category_scores_gemma":[0.0001546502,0.0002123157,0.0002728046,0.0001263799,0.0003712279,0.0004099241,0.000498214,0.00038832,0.0002666878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005696499,"about_ca_system_score_gemma":0.0002681776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000570908,"about_ca_topic_score_gemma":0.001245048,"domain_scores_codex":[0.9998974,0.00001123099,0.000009874956,0.00002728839,0.00002996029,0.00002430804],"domain_scores_gemma":[0.9998759,0.00001280385,0.0000309092,0.00001444987,0.0000158178,0.00005015182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001984002,0.000006912931,0.0004849684,0.00004118625,0.000005685136,0.00005272577,0.00001752283,0.00004805715,0.9978846,0.0002655521,0.00002280914,0.0009715864],"study_design_scores_gemma":[0.00003791965,0.0001542505,0.03337221,0.000009980654,0.00004346489,0.0008844731,0.00006448276,0.001206081,0.960972,0.000259266,0.002982248,0.0000136424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951101,0.002209798,0.001388435,0.00006974602,0.00001114404,0.000008896807,0.0002222239,0.00005456404,0.0009250026],"genre_scores_gemma":[0.9961915,0.0005394951,0.001507419,0.00004687852,0.000005202702,0.00001758007,0.0005344905,0.00002113095,0.001136256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007515502,"threshold_uncertainty_score":0.004133165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01773940336834913,"score_gpt":0.2425272284950095,"score_spread":0.2247878251266604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}