{"id":"W2160111029","doi":"10.2337/dc11-0641","title":"Validation of the Diabetes Prevention Trial–Type 1 Risk Score in the TrialNet Natural History Study","year":2011,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Juvenile Diabetes Research Foundation International; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Medicine; Cumulative incidence; Type 2 diabetes; Diabetes mellitus; Receiver operating characteristic; Incidence (geometry); Type 1 diabetes; Natural history; Internal medicine; Risk assessment; Cohort; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0312496,0.000541757,0.0008053297,0.0008847618,0.0003466348,0.001304367,0.000662275,0.0005456518,0.0009408551],"category_scores_gemma":[0.06689511,0.0002242876,0.0006152059,0.0009025154,0.0005606725,0.0006317092,0.001044906,0.0006201055,0.0003219594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004618807,"about_ca_system_score_gemma":0.0008553467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00181641,"about_ca_topic_score_gemma":0.002974624,"domain_scores_codex":[0.9800447,0.01580014,0.0009251655,0.001319313,0.001697494,0.0002131695],"domain_scores_gemma":[0.9625374,0.02143931,0.007697111,0.003846101,0.003485454,0.0009946098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003785276,0.0001089182,0.9826554,0.0001033051,0.0007273889,0.00006249055,0.0001119896,0.001091843,0.0002678141,0.000228423,0.000862846,0.009994371],"study_design_scores_gemma":[0.001044919,0.001503056,0.9811494,0.0001288868,0.0007497693,0.0004261093,0.00007916891,0.0101265,0.0005062505,0.0008692144,0.003382327,0.00003433745],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860131,0.001807377,0.004342061,0.0004555036,0.0001797223,0.0003460422,0.002806264,0.00004448519,0.004005432],"genre_scores_gemma":[0.9940047,0.0002245724,0.002666757,0.0001816734,0.00008077069,0.0002596536,0.002131274,0.0000158018,0.0004348018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0312496,"threshold_uncertainty_score":0.1652656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814589667949278,"score_gpt":0.2347446607464968,"score_spread":0.216598764067004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}