{"id":"W2160111029","doi":"10.2337/dc11-0641","title":"Validation of the Diabetes Prevention Trial–Type 1 Risk Score in the TrialNet Natural History Study","year":2011,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Juvenile Diabetes Research Foundation International; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Medicine; Cumulative incidence; Type 2 diabetes; Diabetes mellitus; Receiver operating characteristic; Incidence (geometry); Type 1 diabetes; Natural history; Internal medicine; Risk assessment; Cohort; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004998419,0.0001376168,0.0001755111,0.00003851523,0.00006035297,0.00001089695,0.0003682616,0.0001006868,0.00001943933],"category_scores_gemma":[0.0003317901,0.00008821843,0.0001672378,0.0001634299,0.00006411482,0.000007772156,0.00007597521,0.0001420732,0.000003556854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003629869,"about_ca_system_score_gemma":0.00006818121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003039696,"about_ca_topic_score_gemma":0.00007796996,"domain_scores_codex":[0.9985567,0.0005522384,0.0002651966,0.0002304262,0.000180825,0.0002146348],"domain_scores_gemma":[0.9991874,0.0000335425,0.0002571589,0.0004000448,0.000104464,0.00001739555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003121286,0.0003810169,0.9843254,0.000022034,0.0001071703,1.220049e-7,0.002771053,0.00000901869,0.008242123,0.000006892038,0.00127445,0.002548562],"study_design_scores_gemma":[0.0279755,0.004230591,0.8131608,0.0000939602,0.0005051487,5.099366e-8,0.0139842,0.00002642371,0.1340283,0.0004047098,0.005032398,0.0005578829],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950961,0.002564838,1.627937e-7,0.00001187128,0.0007732853,0.0009772093,0.00002232029,0.000006939816,0.0005472616],"genre_scores_gemma":[0.9994931,0.0000301196,0.000008371938,0.00008001189,0.00008548916,0.00007777417,0.0001378324,0.00001512275,0.00007215617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1711646,"threshold_uncertainty_score":0.3597443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814589667949278,"score_gpt":0.2347446607464968,"score_spread":0.216598764067004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}