{"id":"W2160118258","doi":"10.1096/fj.05-4712fje","title":"Pro‐apoptotic effect of endogenous H <sub>2</sub> S on human aorta smooth muscle cells","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":303,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apoptosis; Vascular smooth muscle; Cystathionine gamma-lyase; Transfection; Endogeny; Viability assay; TUNEL assay; MAPK/ERK pathway; Cell growth; Molecular biology; Chemistry; Cell biology; Cyclin D1; Signal transduction; Cancer research; Biology; Cystathionine beta synthase; Enzyme; Gene; Biochemistry; Cysteine; Cell cycle; Endocrinology; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006250626,0.0002074262,0.000235354,0.00005992229,0.0002415779,0.00002675395,0.0004352155,0.0001438709,0.00001831461],"category_scores_gemma":[0.00004488354,0.0001361806,0.0001955178,0.00007517864,0.0002013163,0.000002530274,0.00009047263,0.0002799968,0.00002154335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002875251,"about_ca_system_score_gemma":0.00005026606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001889302,"about_ca_topic_score_gemma":0.00001540854,"domain_scores_codex":[0.9985514,0.0003532573,0.0003363606,0.0002263997,0.0001832865,0.0003493484],"domain_scores_gemma":[0.9990931,0.00008048501,0.0002575228,0.0004416285,0.00006430416,0.00006299157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000125468,0.00008467452,0.0007285652,0.00001191084,0.00004987151,0.00001941039,0.00001845161,0.0002262714,0.9960501,0.00003322899,0.0008393257,0.001812702],"study_design_scores_gemma":[0.0007864926,0.00176244,0.001893782,0.0000190904,0.00005020102,0.0001495242,0.00001096892,0.000007069879,0.9942448,0.0002021166,0.0007264388,0.0001471168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970341,0.000368686,0.00008279402,0.00004104979,0.0003653862,0.0002161268,0.00001220803,0.000009873676,0.001869761],"genre_scores_gemma":[0.9989233,0.00005169102,0.00004504645,0.00009916216,0.0007577276,0.00000851432,0.00002951989,0.00002966957,0.00005537898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001889176,"threshold_uncertainty_score":0.5553284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01660518610071955,"score_gpt":0.246176824539258,"score_spread":0.2295716384385384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}