{"id":"W2160119714","doi":"10.3390/biology2030976","title":"The Role of Nuclear Bodies in Gene Expression and Disease","year":2013,"lang":"en","type":"article","venue":"Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Institute of Human Development, Child and Youth Health; Hospital for Sick Children; University of British Columbia; National Institutes of Health; Michael Smith Health Research BC","keywords":"Biology; Cajal body; Transcription factories; Nucleolus; Ribosome biogenesis; Gene expression; Cell biology; Stress granule; Histone; Cell nucleus; Genetics; Spliceosome; Gene; RNA; RNA splicing; Ribosome; Transcriptional regulation; Messenger RNA; Nucleus; Translation (biology)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000376429,0.0002728868,0.0005232958,0.0005583506,0.0002561666,0.0007941126,0.0003110989,0.0006102645,0.001326174],"category_scores_gemma":[0.0002905273,0.0001107427,0.000229042,0.0004447533,0.000675971,0.0008352686,0.0005329545,0.0005571314,0.0007402034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003950883,"about_ca_system_score_gemma":0.0003381562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003374714,"about_ca_topic_score_gemma":0.0004092084,"domain_scores_codex":[0.9998379,0.00003793298,0.00001935289,0.00003166344,0.00005357531,0.00001970435],"domain_scores_gemma":[0.9998614,0.00005648537,0.00002921284,0.00001004326,0.00002457351,0.00001834026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003257196,0.00004595383,0.00304882,0.004408571,0.0001610182,0.003449783,0.0007534494,0.0009360167,0.09606352,0.04108874,0.02535593,0.8243624],"study_design_scores_gemma":[0.00001253264,0.0001951665,0.005958472,0.0008719143,0.0001046097,0.009339332,0.0003020239,0.0002526847,0.01583998,0.01939846,0.9476888,0.00003599072],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005650366,0.9820935,0.00337763,0.001659208,0.0008274026,0.000007311348,0.00006346212,0.000065868,0.006255348],"genre_scores_gemma":[0.03538659,0.9561037,0.00266128,0.0005804422,0.0007674529,0.00001441014,0.0001058078,0.00001585269,0.004364549],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001326174,"threshold_uncertainty_score":0.004436493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005773556856783765,"score_gpt":0.2427405943285704,"score_spread":0.2369670374717866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}